Department of Research & Evaluation, SC Kaiser Permanente

Research Scientists

Karen J. Coleman, PhD, MS

Research Scientist II
Research & Evaluation
100 S. Los Robles Ave
Pasadena, CA 91101-2453
Phone: 626-564-3580
Email Address: Karen.J.Coleman@kp.org

Back to Research Scientists Team

Other Affiliation

Adjunct Associate Professor, Keck School of Medicine, Department of Preventive Medicine, Los Angeles, California

Education

PhD, Biopsychology, University of Georgia, Athens, Georgia

MS, Biopsychology, University of Georgia, Athens, Georgia

BS, Zoology, Washington State University, Pullman, Washington

Research Interests

I study the behavioral, social, and environmental determinants of success after weight loss surgery and interventions in primary care for adult depression. My main areas of interest are health equity and the study of patient, provider, and system-level factors that lead to successful interventions for physical and emotional wellness. I direct one of the largest weight loss registries in the US used for both patient care and research. I also direct a population management registry for the KPSC depression care management program. I have a half time appointment in KPSC clinical operations where I serve on the regional leadership teams for bariatric surgery and depression care.

Publications Studies

Are wishes for death or suicidal ideation symptoms of depression in older adults?
Rossom RC, Simon GE, Coleman KJ, Beck A, Oliver M, Stewart C, Ahmedani B
Aging Ment Health. 2018; Jan 17:1-7 PubMed Abstract

Care Pathways Before First Diagnosis of a Psychotic Disorder in Adolescents and Young Adults.
Simon GE, Stewart C, Hunkeler EM, Yarborough BJ, Lynch F, Coleman KJ, Beck A, Operskalski BH, Penfold RB, Carrell DS
Am J Psychiatry. 2018; 175:434-442 PubMed Abstract

Comparative effectiveness of bariatric procedures among adolescents: the PCORnet bariatric study.
Inge TH, Coley RY, Bazzano LA, Xanthakos SA, McTigue K, Arterburn D, Williams N, Wellman R, Coleman KJ, Courcoulas A, Desai NK, Anau J, Pardee R, Toh S, Janning C, Cook A, Sturtevant J, Horgan C, Zebrick AJ, Michalsky M.
SOARD. 2018; 14(9):1374-1386 PubMed Abstract

Mortality Rates After the First Diagnosis of Psychotic Disorder in Adolescents and Young Adults.
Simon GE, Stewart C, Yarborough BJ, Lynch F, Coleman KJ, Beck A, Operskalski BH, Penfold RB, Hunkeler EM
JAMA Psychiatry. 2018; 75:254-260 PubMed Abstract

Near Real-time Surveillance for Consequences of Health Policies Using Sequential Analysis.
Lu CY, Penfold RB, Toh S, Sturtevant JL, Madden JM, Simon G, Ahmedani BK, Clarke G, Coleman KJ, Copeland LA, Daida YG, Davis RL, Hunkeler EM, Owen-Smith A, Raebel MA, Rossom R, Soumerai SB, Kulldorff M
Med Care. 2018; 56:365-372 PubMed Abstract

Predicting Suicide Attempts for Racial and Ethnic Groups of Patients During Routine Clinical Care.
Coleman KJ, Johnson E, Ahmedani BK, Beck A, Rossom RC, Shortreed SM, Simon GE
Suicide & Life-Threatening Behavior. 2018 PubMed Abstract

Treatment Initiation for New Episodes of Depression in Primary Care Settings.
Waitzfelder B, Stewart C, Coleman KJ, Rossom R, Ahmedani BK, Beck A, Zeber JE, Daida YG, Trinacty C, Hubley S, Simon GE
J Gen Intern Med. 2018; 33(8):1283-1291 PubMed Abstract

Understanding the Capacity for Exercise in Post-Bariatric Patients.
Coleman KJ, Caparosa SL, Nichols JF, Fujioka K, Koebnick C, McCloskey KN, Xiang AH, Ngor EW, Levy SS
Obes Surg. 2017; 27:51-58 PubMed Abstract

Understanding the experience of care managers and relationship with patient outcomes: the COMPASS initiative.
Coleman KJ, Hemmila T, Valenti MD, Smith N, Quarrell R, Ruona LK, Brandenfels E, Hann B, Hinnenkamp T, Parra MD, Monkman J, Vos S, Rossom RC
Gen Hosp Psychiatry. 2017; 44:86-90 PubMed Abstract

The COMPASS initiative: description of a nationwide collaborative approach to the care of patients with depression and diabetes and/or cardiovascular disease.
Coleman KJ, Magnan S, Neely C, Solberg L, Beck A, Trevis J, Heim C, Williams M, Katzelnick D, Unützer J, Pollock B, Hafer E, Ferguson R, Williams S
Gen Hosp Psychiatry. 2017; 44:69-76 PubMed Abstract

Psychotropic Medication Use among Insured Children with Autism Spectrum Disorder.
Madden JM, Lakoma MD, Lynch FL, Rusinak D, Owen-Smith AA, Coleman KJ, Quinn VP, Yau VM, Qian YX, Croen LA
J Autism Dev Disord. 2017; 47:144-154 PubMed Abstract

Suicidal ideation reported on the PHQ9 and risk of suicidal behavior across age groups.
Rossom RC, Coleman KJ, Ahmedani BK, Beck A, Johnson E, Oliver M, Simon GE
J Affect Disord. 2017; 215:77-84 PubMed Abstract

Mental illness in bariatric surgery: A cohort study from the PORTAL network.
Fisher D, Coleman KJ, Arterburn DE, Fischer H, Yamamoto A, Young DR, Sherwood NE, Trinacty CM, Lewis KH
Obesity (Silver Spring). 2017; 25:850-856 PubMed Abstract

Clinician burnout and satisfaction with resources in caring for complex patients.
Whitebird RR, Solberg LI, Crain AL, Rossom RC, Beck A, Neely C, Dreskin M, Coleman KJ
Gen Hosp Psychiatry. 2017; 44:91-95 PubMed Abstract

Between-visit changes in suicidal ideation and risk of subsequent suicide attempt.
Simon GE, Shortreed SM, Johnson E, Beck A, Coleman KJ, Rossom RC, Whiteside US, Operskalski BH, Penfold RB
Depress Anxiety. 2017; 34:794-800 PubMed Abstract

Comparative effectiveness of sleeve gastrectomy versus Roux-en-Y gastric bypass for weight loss and safety outcomes in older adults.
Casillas RA, Kim B, Fischer H, Zelada Getty JL, Um SS, Coleman KJ
Surg Obes Relat Dis. 2017; 13:1476-1483 PubMed Abstract

Estimated GFR Before and After Bariatric Surgery in CKD.
Imam TH, Fischer H, Jing B, Burchette R, Henry S, DeRose SF, Coleman KJ
Am J Kidney Dis. 2017; 69:380-388 PubMed Abstract

First Presentation With Psychotic Symptoms in a Population-Based Sample.
Simon GE, Coleman KJ, Yarborough BJH, Operskalski B, Stewart C, Hunkeler EM, Lynch F, Carrell D, Beck A
Psychiatr Serv. 2017; 68:456-461 PubMed Abstract

Impact of a national collaborative care initiative for patients with depression and diabetes or cardiovascular disease.
Rossom RC, Solberg LI, Magnan S, Crain AL, Beck A, Coleman KJ, Katzelnick D, Williams MD, Neely C, Ohnsorg K, Whitebird R, Brandenfels E, Pollock B, Ferguson R, Williams S, Unützer J
Gen Hosp Psychiatry. 2017; 44:77-85 PubMed Abstract

Health Services Utilization Among Children With and Without Autism Spectrum Disorders.
Cummings JR, Lynch FL, Rust KC, Coleman KJ, Madden JM, Owen-Smith AA, Yau VM, Qian Y, Pearson KA, Crawford PM, Massolo ML, Quinn VP, Croen LA
J Autism Dev Disord. 2016; 46:910-920 PubMed Abstract

ANTIDEPRESSANT ADHERENCE ACROSS DIVERSE POPULATIONS AND HEALTHCARE SETTINGS.
Rossom RC, Shortreed S, Coleman KJ, Beck A, Waitzfelder BE, Stewart C, Ahmedani BK, Zeber JE, Simon GE
Depress Anxiety. 2016; 33:765-74 PubMed Abstract

Long-term Microvascular Disease Outcomes in Patients With Type 2 Diabetes After Bariatric Surgery: Evidence for the Legacy Effect of Surgery.
Coleman KJ, Haneuse S, Johnson E, Bogart A, Fisher D, O'Connor PJ, Sherwood NE, Sidney S, Theis MK, Anau J, Schroeder EB, O'Brien R, Arterburn D
Diabetes Care. 2016; 39:1400-7 PubMed Abstract

Patient-centered physical activity coaching in COPD (Walk On!): A study protocol for a pragmatic randomized controlled trial.
Nguyen HQ, Bailey A, Coleman KJ, Desai S, Fan VS, Gould MK, Maddock L, Miller K, Towner W, Xiang AH, Moy ML
Contemp Clin Trials. 2016; 46:18-29 PubMed Abstract

Risk of suicide attempt and suicide death following completion of the Patient Health Questionnaire depression module in community practice.
Simon GE, Coleman KJ, Rossom RC, Beck A, Oliver M, Johnson E, Whiteside U, Operskalski B, Penfold RB, Shortreed SM, Rutter C
J Clin Psychiatry. 2016; 77:221-7 PubMed Abstract

Racial-Ethnic Differences in Psychiatric Diagnoses and Treatment Across 11 Health Care Systems in the Mental Health Research Network.
Coleman KJ, Stewart C, Waitzfelder BE, Zeber JE, Morales LS, Ahmed AT, Ahmedani BK, Beck A, Copeland LA, Cummings JR, Hunkeler EM, Lindberg NM, Lynch F, Lu CY, Owen-Smith AA, Trinacty CM, Whitebird RR, Simon GE
Psychiatr Serv. 2016; 67:749-57 PubMed Abstract

The triad of kidney, obesity, and bariatric surgery.
Imam TH, Coleman KJ
Saudi J Kidney Dis Transpl. 2016; 27:875-884 PubMed Abstract

Psychiatric comorbidity and 30-day readmissions after hospitalization for heart failure, AMI, and pneumonia.
Ahmedani BK, Solberg LI, Copeland LA, Fang-Hollingsworth Y, Stewart C, Hu J, Nerenz DR, Williams LK, Cassidy-Bushrow AE, Waxmonsky J, Lu CY, Waitzfelder BE, Owen-Smith AA, Coleman KJ, Lynch FL, Ahmed AT, Beck A, Rossom RC, Simon GE
Psychiatr Serv. 2015; 66:134-40 PubMed Abstract

Prevalence and Predictors of Complementary and Alternative Medicine Use in a Large Insured Sample of Children with Autism Spectrum Disorders.
Owen-Smith AA, Bent S, Lynch FL, Coleman KJ, Yau VM, Pearson KA, Massolo ML, Quinn V, Croen LA
Res Autism Spectr Disord. 2015; 17:40-51 PubMed Abstract

Antidepressants are not overprescribed for mild depression.
Simon GE1, Rossom RC, Beck A, Waitzfelder BE, Coleman KJ, Stewart C, Operskalski B, Penfold RB, Shortreed SM
J Clin Psychiatry. 2015; 76:1627-32 PubMed Abstract

Association of maternal diabetes with autism in offspring.
Xiang AH, Wang X, Martinez MP, Walthall JC, Curry ES, Page K, Buchanan TA, Coleman KJ, Getahun D
JAMA. 2015; 313:1425-34 PubMed Abstract

Impact of bariatric surgery on life expectancy in severely obese patients with diabetes: a decision analysis.
Schauer DP, Arterburn DE, Livingston EH, Coleman KJ, Sidney S, Fisher D, O'Connor P, Fischer D, Eckman MH
Ann Surg. 2015; 261:914-9 PubMed Abstract

Adjusting Antidepressant Quality Measures for Race and Ethnicity.
Simon GE, Coleman KJ, Waitzfelder BE, Beck A, Rossom RC, Stewart C, Penfold RB
JAMA Psychiatry. 2015; 72:1055-6 PubMed Abstract

Validation of Autism Spectrum Disorder Diagnoses in Large Healthcare Systems with Electronic Medical Records.
Coleman KJ, Lutsky MA, Yau V, Qian Y, Pomichowski ME, Crawford PM, Lynch FL, Madden JM, Owen-Smith A, Pearson JA, Pearson KA, Rusinak D, Quinn VP, Croen LA
J Autism Dev Disord. 2015; 45:1989-96 PubMed Abstract

Fundraising, celebrations and classroom rewards are substantial sources of unhealthy foods and beverages on public school campuses.
Caparosa SL, Shordon M, Santos AT, Pomichowski ME, Dzewaltowski DA, Coleman KJ
Public Health Nutr. 2014; 17:1205-13 PubMed Abstract

Gender and Racial/Ethnic Background Predict Weight Loss after Roux-en-Y Gastric Bypass Independent of Health and Lifestyle Behaviors.
Coleman KJ, Brookey J
Obes Surg. 2014; 24:1729-36 PubMed Abstract

How complete are E-codes in commercial plan claims databases?
Lu CY, Stewart C, Ahmed AT, Ahmedani BK, Coleman K, Copeland LA, Hunkeler EM, Lakoma MD, Madden JM, Penfold RB, Rusinak D, Zhang F, Soumerai SB
Pharmacoepidemiol Drug Saf. 2014; 23:218-20 PubMed Abstract

Associations between physical activity and 30-day readmission risk in chronic obstructive pulmonary disease.
Nguyen HQ, Chu L, Amy Liu IL, Lee JS, Suh D, Korotzer B, Yuen G, Desai S, Coleman KJ, Xiang AH, Gould MK
Ann Am Thorac Soc. 2014; 11:695-705 PubMed Abstract

Associations between physical activity and cardiometabolic risk factors assessed in a Southern California health care system, 2010-2012.
Young DR, Coleman KJ, Ngor E, Reynolds K, Sidell M, Sallis RE
Prev Chronic Dis. 2014; 11:E219 PubMed Abstract

Changes in antidepressant use by young people and suicidal behavior after FDA warnings and media coverage: quasi-experimental study.
Lu CY, Zhang F, Lakoma MD, Madden JM, Rusinak D, Penfold RB, Simon G, Ahmedani BK, Clarke G, Hunkeler EM, Waitzfelder B, Owen-Smith A, Raebel MA, Rossom R, Coleman KJ, Copeland LA, Soumerai SB
BMJ. 2014; 348:g3596 PubMed Abstract

Metabolic syndrome is less likely to resolve in Hispanics and non-Hispanic blacks after bariatric surgery.
Coleman KJ, Huang YC, Koebnick C, Reynolds K, Xiang AH, Black MH, Alskaf S
Ann Surg. 2014; 259:279-85 PubMed Abstract

National prevalence of receipt of antidepressant prescriptions by persons without a psychiatric diagnosis.
Simon GE, Stewart C, Beck A, Ahmedani BK, Coleman KJ, Whitebird RR, Lynch F, Owen-Smith AA, Waitzfelder BE, Soumerai SB, Hunkeler EM
Psychiatr Serv. 2014; 65:944-6 PubMed Abstract

Optimal management of diabetes among overweight and obese adults.
Ryan DS, Coleman KJ, Lawrence JM, Harrison TN, Reynolds K
Am J Manag Care. 2014; 20:e1-7 PubMed Abstract

Three-year weight outcomes from a bariatric surgery registry in a large integrated healthcare system.
Coleman KJ, Huang YC, Hendee F, Watson HL, Casillas RA, Brookey J
Surg Obes Relat Dis. 2014; 10:396-403 PubMed Abstract

Use of antipsychotic medications in pediatric populations: what do the data say?
Penfold RB, Stewart C, Hunkeler EM, Madden JM, Cummings JR, Owen-Smith AA, Rossom RC, Lu CY, Lynch FL, Waitzfelder BE, Coleman KJ, Ahmedani BK, Beck AL, Zeber JE, Simon GE
Curr Psychiatry Rep. 2013; 15:426 PubMed Abstract

Race and ethnicity data quality and imputation using U.S. Census data in an integrated health system: the Kaiser Permanente Southern California experience.
Derose SF, Contreras R, Coleman KJ, Koebnick C, Jacobsen SJ
Med Care Res Rev. 2013; 70:330-45 PubMed Abstract

Comparative effectiveness of bariatric surgery vs. nonsurgical treatment of type 2 diabetes among severely obese adults.
Arterburn D, Bogart A, Coleman KJ, Haneuse S, Selby JV, Sherwood NE, Sidney S, Theis MK, Campos GM, McCulloch D, O'Connor PJ
Obes Res Clin Pract. 2013; 7:e235-320 PubMed Abstract

A Multisite Study of Long-term Remission and Relapse of Type 2 Diabetes Mellitus Following Gastric Bypass.
Arterburn DE, Bogart A, Sherwood NE, Sidney S, Coleman KJ, Haneuse S, O'Connor PJ, Theis MK, Campos GM, McCulloch D, Selby J
Obes Surg. 2013; 23:93-102 PubMed Abstract

The authors respond: a multisite study of long-term remission and relapse of type 2 diabetes mellitus following gastric bypass.
Arterburn DE, Campos GM, Haneuse S, Sherwood NE, Bogart A, Sidney S, Coleman KJ, Theis MK, O'Connor P, Fisher D
Obes Surg. 2013; 23:1456-7 PubMed Abstract

Cohort profile: the KPSC Children's Health Study, a population-based study of 920 000 children and adolescents in southern California.
Koebnick C, Coleman KJ, Black MH, Smith N, Der-Sarkissian JK, Jacobsen SJ, Porter AH
Int J Epidemiol. 2012; 41:627-33 PubMed Abstract

Evaluation of a multi-component group exercise program for adults with arthritis: Fitness and Exercise for People with Arthritis (FEPA).
Levy SS, Macera CA, Hootman JM, Coleman KJ, Lopez R, Nichols JF, Marshall SJ, Ainsworth BA, Ji M
Disabil Health J. 2012; 5:305-11 PubMed Abstract

Implementation of clinical practice guidelines for pediatric weight management.
Coleman KJ, Hsii AC, Koebnick C, Alpern AF, Bley B, Yousef M, Shih EM, Trimble-Cox KJ, Smith N, Porter AH, Woods SD
J Pediatr. 2012; 160:918-922.e1 PubMed Abstract

Initial validation of an exercise "vital sign" in electronic medical records.
Coleman KJ, Ngor E, Reynolds K, Quinn VP, Koebnick C, Young DR, Sternfeld B, Sallis RE
Med Sci Sports Exerc. 2012; 44:2071-2076 PubMed Abstract

Readiness to Be Physically Active and Self-Reported Physical Activity in Low-Income Latinas, California WISEWOMAN, 2006-2007.
Coleman KJ, Farrell MA, Rocha DA, Hayashi T, Hernandez M, Wolf J, Lindsay S
Prev Chronic Dis. 2012; 9:E87 PubMed Abstract

The healthy options for nutrition environments in schools (Healthy ONES) group randomized trial: using implementation models to change nutrition policy and environments in low income schools.
Coleman KJ, Shordon M, Caparosa SL, Pomichowski ME, Dzewaltowski DA
Int J Behav Nutr Phys Act. 2012; 9:80 PubMed Abstract

The role of community health workers (CHWs) in health promotion research: ethical challenges and practical solutions.
Terpstra J, Coleman KJ, Simon G, Nebeker C
Health Promot Pract. 2011; 12:86-93 PubMed Abstract

Teen peer educators and diabetes knowledge of low-income fifth grade students.
Coleman KJ, Clark AY, Shordon M, Ocana LL, Walker C, Araujo RA, Oratowski-Coleman J, Philis-Tsimikas A
J Community Health. 2011; 36:23-6 PubMed Abstract

Ethnic, Gender, and BMI Differences in Athletic Identity in Children and Adolescents.
Anderson CB, Mâsse LC, Zhang H, Coleman KJ, Chang S
J Phys Act Health. 2011; 8:200-9 PubMed Abstract

Do gastric bypass patient characteristics, behavior, and health differ depending upon how successful weight loss is defined?
Coleman KJ, Toussi R, Fujioka K
Obes Surg. 2010; 20:1385-92 PubMed Abstract

HOP'N after-school project: an obesity prevention randomized controlled trial.
Dzewaltowski DA, Rosenkranz RR, Geller KS, Coleman KJ, Welk GJ, Hastmann TJ, Milliken GA
Int J Behav Nutr Phys Act. 2010; 7:90 PubMed Abstract

Body weight and height data in electronic medical records of children.
Smith N, Coleman KJ, Lawrence JM, Quinn VP, Getahun D, Reynolds K, Chen W, Porter AH, Jacobsen SJ, Koebnick C
Int J Pediatr Obes. 2010; 5:237-42 PubMed Abstract

Outcomes from a culturally tailored diabetes prevention program in Hispanic families from a low-income school: Horton Hawks Stay Healthy (HHSH).
Coleman KJ, Ocana LL, Walker C, Araujo RA, Gutierrez V, Shordon M, Oratowski-Coleman J, Philis-Tsimikas A
Diabetes Educ. 2010; 36:784-92 PubMed Abstract

Prevalence of extreme obesity in a multiethnic cohort of children and adolescents.
Koebnick C, Smith N, Coleman KJ, Getahun D, Reynolds K, Quinn VP, Porter AH, Der-Sarkissian JK, Jacobsen SJ
J Pediatr. 2010; 157:26-31.e2 PubMed Abstract

Pre- and postsurgery behavioral compliance, patient health, and postbariatric surgical weight loss.
Toussi R, Fujioka K, Coleman KJ
Obesity (Silver Spring). 2009; 17:996-1002 PubMed Abstract

Patient-physician language concordance: a strategy for meeting the needs of spanish-speaking patients in primary care.
Kanter MH, Abrams KM, Carrasco MR, Spiegel NH, Vogel RS, Coleman KJ
Perm J. 2009; 13:79-84 PubMed Abstract

Papanicolaou screening behavior in mothers and human papillomavirus vaccine uptake in adolescent girls.
Chao C, Slezak JM, Coleman KJ, Jacobsen SJ
Am J Public Health. 2009; 99:1137-42 PubMed Abstract

Trends in nonalcoholic fatty liver disease-related hospitalizations in US children, adolescents, and young adults.
Koebnick C, Getahun D, Reynolds K, Coleman KJ, Porter AH, Lawrence JM, Punyanitya M, Quinn VP, Jacobsen SJ
J Pediatr Gastroenterol Nutr. 2009; 48:597-603 PubMed Abstract

Contribution of Athletic Identity to Child and Adolescent Physical Activity.
Anderson CB, Mâsse LC, Zhang H, Coleman KJ, Chang S
Am J Prev Med. 2009; 37:220-226 PubMed Abstract

What do I do with my morbidly obese patient? A detailed case study of bariatric surgery in kaiser permanente southern california.
Shafipour P, Der-Sarkissian JK, Hendee FN, Coleman KJ
Perm J. 2009; 13:56-63 PubMed Abstract

Adaptation and validation of the athletic identity questionnaire-adolescent for use with children.
Anderson CB, Coleman KJ
J Phys Act Health. 2008; 5:539-558 PubMed Abstract

Physical activity and healthy eating in the after-school environment.
Coleman KJ, Geller KS, Rosenkranz RR, Dzewaltowski DA
J Sch Health. 2008; 78:633-640 PubMed Abstract

Physical activity, weight status, and neighborhood characteristics of dog walkers.
Coleman KJ, Rosenberg DE, Conway TL, Sallis JF, Saelens BE, Frank LD, Cain K
Prev Med. 2008; 47:309-312 PubMed Abstract

Characteristics of self-selected portion size in young adults.
Burger KS, Kern M, Coleman KJ
J Am Diet Assoc. 2007; 107:611-8 PubMed Abstract

Care Partners: Bridging Families, Clinics, and Communities to Advance Late-Life Depression Care

Karen J. Coleman, PhD, MS, Principal Investigator

Funding source:

Funding Years: 2018-2021

The major goals of this project are to 1) Use the Primary Care – CBO Partnership funding opportunity to establish a collaborative, sustainable working relationship between Kaiser Permanente Southern California (KPSC), the largest healthcare provider in Southern California, and Healthy African American Families (HAAF) II, the lead community agency for the Community Partners in Care (CPIC) initiative which helped establish the evidence base for a multi-sector, community-engagement-based approach to collaborative care for depression and 2) to improve the care and outcomes for older adult patients in the KPSC Depression Care Management (DCM) program and address several DCM program needs as identified by previous work in this area.

https://aims.uw.edu/care-partners/

Building Capacity for Stakeholder Engagement in the Mental Health Research Network

Karen J. Coleman, PhD, MS, Principal Investigator

Funding source: Patient-Centered Outcomes Research Institute (PCORI)

Funding Years: 2018-2020

This Eugene Washington engagement award will be used primarily to support the development of the involvement of our patients with mental health conditions, their caregivers and/or families, and national mental health community and advocacy groups who represent them in all phases of mental health research. The goals of this project are to: 1) Add the patient, caregiver, and family stakeholder voice and the community and advocacy groups who represent them to the national Mental Health Research Network (MHRN) executive leadership team to develop a shared direction for the network and a shared national voice for mental health comparative effectiveness research (CER); 2) Develop and pilot a strategy for stakeholder engagement within one MHRN-affiliated health system and the communities it serves to identify priorities for mental health CER; and 3) Develop and submit at least one new research proposal using the processes used in #1 and #2 at the end of the engagement award.

Long-term Benefits and Risks of Bariatric Surgery in Integrated Care Systems (DURABLE)

Karen J. Coleman, PhD, MS, Principal Investigator

Funding source:

This is a multi-site, multiple PI (Arterburn/Coleman) study funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to achieve the following aims: 1) determine the rates of weight regain, bariatric surgical reoperation/reintervention, and death, and the predictors of these adverse events over a 5 - 10 year period after bariatric surgery; 2) determine the improvement in kidney function and the predictors of the improvement of kidney function over a 5 - 10 year period after surgery; and 3) investigate the potential biases in studies of bariatric surgery using electronic healthcare data.

An Evaluation of the National Zero Suicide Model across Learning Healthcare Systems

Karen J. Coleman, PhD, MS, Site Principal Investigator

Funding source: National Institute of Mental Health (NIMH)

Funding Years: 2017-2022

Our project seeks to develop metrics to measure fidelity and outcomes for the National Zero Suicide Model components implemented in each system using electronic health records and insurance claims data sources that are easily extractable and generalizable to other systems. Then, we propose to use these metrics to conduct fidelity and outcome evaluation of the various Zero Suicide Initiative approaches in each system using Interrupted Time Series Designs, which are among the strongest, pragmatic designs appropriate for evaluating care system intervention and policy changes in ‘Learning Healthcare Systems.’ We hypothesize that the implementation of various National Zero Suicide Model components will significantly reduce suicidal behavior within and across the participating systems. We seek to accomplish the following aims: 1) Collaborate with health system leaders to develop EHR metrics to measure specific quality improvement targets and care processes tailored to local Zero Suicide Initiative implementation; 2) examine the fidelity of the specific Zero Suicide Initiative care processes implemented in each system; and 3) investigate suicide attempt and mortality outcomes within and across Zero Suicide Initiative healthcare system models.

http://zerosuicide.sprc.org/

Effectiveness of Gastric Sleeve vs. Gastric Bypass for Cardiovascular Disease (ENGAGE-CVD)

Karen J. Coleman, PhD, MS, Principal Investigator

Funding source: National Heart, Lung, and Blood Institute (NHLBI)

Funding Years: 2016-2020

This study will include only bariatric surgery patients from Kaiser Permanente Southern California and is designed to achieve the following aims: 1) compare the effectiveness of vertical sleeve gastrectomy (VSG) and Roux-en-Y Gastric Bypass (RYGB) in remission of risk factors for cardiovascular disease (CVD) and reduction in overall CVD risk using advanced statistical and econometric techniques.; 2) compare VSG and RYGB surgical safety using similar methods; and 3) understand the treatment effect heterogeneity in remission of CVD risk factors, reduction in overall CVD risk, and safety outcomes for patients with different racial/ethnic backgrounds, sexes, and disease burdens at the time of surgery.

Predictors of Weight Loss Failure and Regain in Bariatric Patients (BELONG)

Karen J. Coleman, PhD, MS, Principal Investigator

Funding source: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Funding Years: 2016-2021

This study will include only bariatric surgery patients from Kaiser Permanente Southern California right before they have surgery and then for three years after having surgery. The aims of this study are to determine over a 3-year follow up period how demographic, behavioral, psychosocial, and perceived environmental pre-surgical factors, and post-surgical behavioral and psychosocial factors predict a) weight loss trajectory and b) weight loss success. To understand the variability in weight loss using qualitative methods in cross-sectional samples of post-operative survey respondents and use these findings to inform mediational models addressing aim 1; and over the follow-up period, study the development of adverse psychosocial consequences and determine how they relate to a) overall weight loss and b) weight loss success.

PCORnet Bariatric Study

Karen J. Coleman, PhD, MS, Site Principal Investigator

Funding source: Patient-Centered Outcomes Research Institute (PCORI)

Funding Years: 2016-2018

This study is designed to address the following aims in over 30 clinical sites participating in the national Patient-Centered Outcomes Research Network (PCORnet) Bariatric Study: Aim 1: To what extent does weight loss and weight regain differ across bariatric surgical procedures (Roux-en-Y gastric bypass, sleeve gastrectomy, and adjustable gastric banding) at 1, 3, and 5 years? Aim 2: To what extent does bariatric surgery lead to improvements in diabetes risk at 1, 3, and 5 years? Aim 3: What is the frequency of adverse events following different bariatric surgical procedures at 1, 3, and 5 years? Aim 4: To elicit patient preferences around the risks and benefits regarding the choice of (a) whether to undergo bariatric surgery; (b) which bariatric procedure to utilize; and (c) follow-up care after bariatric surgery.

http://www.pcornet.org/obesity-studies-addressing-questions-treatment-prevention/

Mental Health Research Network II

Karen J. Coleman, PhD, MS, Site Principal Investigator

Funding source: National Institute of Mental Health (NIMH)

Funding Years: 2014-2019

We have established a Mental Health Research Network including 13 established public-domain research centers based in integrated not-for-profit health systems. These systems provide care to a diverse population of 10 million people in 11 states, and they share rich and compatible data resources to support a range of effectiveness research. Diversity of member demographics, insurance coverage, and organization of health services make this network an ideal environment for studying variation in care, comparing effectiveness and cost of treatments across practice environments, and studying dissemination and health policies. Participating research centers are experienced in a wide range of clinical areas and research methods. The long-term objectives are to expand the Mental Health Research Network to include additional health systems and external investigators, to conduct multi-site observational and experimental studies of comparative effectiveness, to develop and evaluate methods for dissemination and implementation, and to become a national resource of research methods and effectiveness evidence for researchers, patients, providers and healthcare leaders.

http://hcsrn.org/mhrn/en/

Care of Mental, Physical, and Substance Use Syndromes (COMPASS)

Karen J. Coleman, PhD, MS, Principal Investigator

Funding source: Institute for Clinical Systems Improvement (ICSI)

Funding Years: 2012-2015

KPSC is one of nine sites throughout the country funded by an Innovation Award from the Centers of Medicare and Medicaid to implement a coordinated care model for depressed patients with cardiovascular disease. We have the following goals for this project: 1. To implement in three stages a multiple condition collaborative care management model in primary care clinics of care systems in states. 2. To demonstrate that this model improves care quality, patient experience and health, provider satisfaction, and total healthcare costs for the Medicare and Medicaid patients with the targeted conditions. 3. To develop role descriptions and training for the two new types of workers required for this model – care managers and care consultants. 4. To identify the costs and payment models needed by care systems to sustain and spread this care model.

http://compasscareteams.com/aboutcompass/

The Impact of Bariatric Surgery on Health Outcomes for Obese Patients

Karen J. Coleman, PhD, MS, Principal Investigator

Funding source: Southern California Permanente Medical Group (SCPMG)

Funding Years: 2008-2020

To create and maintain a registry for KPSC patients who have had weight loss surgery since 2004. This registry contains all electronic medical record information for these patients. The registry is used for quality monitoring and improvement, patient care management, outcomes monitoring, and research.

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