About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Nigel Gupta headshot
Nigel Gupta, MD
Principal Investigator
Los Angeles Medical Center

Dr. Nigel Gupta is a cardiologist and electrophysiologist and a principal investigator for clinical trials at the Kaiser Permanente Los Angeles Medical Center. His clinical trials participation includes a worldwide trial to evaluate the safety and effectiveness of a left atrial appendage closure device for patients with atrial fibrillation and a trial evaluating the safety and performance of ventricular defibrillation leads. Dr. Gupta is also an investigator in the federally funded National Cardiovascular ...


Featured Image of News Story Titled: Severe morning sickness associated with higher risk of autism

Severe morning sickness associated with higher risk of autism

Children whose mothers had hyperemesis gravidarum — a severe form of a morning sickness — during pregnancy were 53% more likely to be diagnosed with autism spectrum disorder, according to Kaiser Permanente research published in the American Journal of Perinatology. “This study is important because it suggests that children born to women with hyperemesis may ...

Five questions for Dr. Claudia Nau

Investigator Claudia Nau, PhD, of the Kaiser Permanente Southern California Department of Research & Evaluation, recently published a commentary on the role of predictive models in supporting a comprehensive national Kaiser Permanente social needs strategy. How do social needs affect health? Social needs include things such as whether people have time and money to buy ...

National ACE conference draws health researchers to Pasadena

Speakers gave epidemiologists the tools and inspiration to turn data into research with an impact on clinical practice during the 2019 American College of Epidemiology Annual Meeting, which was hosted by Kaiser Permanente Southern California Department of Research & Evaluation. “The conference was a great success,” said Russell S. Kirby, PhD, MS, of the College ...

Dr. Steven Jacobsen of Kaiser Permanente elected president-elect of the American College of Epidemiology

The Senior Director of Research for Kaiser Permanente Southern California, Steven J. Jacobsen, MD, PhD, has been elected by his peers to the office of president-elect of the American College of Epidemiology (ACE) for the 2020 membership year. He will assume the College’s presidency in 2021. The election results were announced today (Sept. 10, 2019) ...

Online physician ratings may not be accurate

The physician ratings that patients see online may be inaccurate when compared to ratings compiled from surveys conducted internally by health care organizations, according to new research published today (Sept. 17, 2019) in the Journal of General Internal Medicine. “We know that patients often rely on online ratings when choosing doctors,” said Kanu Okike, MD, ...


Featured Division

Clinical Trials Research

Our physician investigators conduct clinical trials in communities across Southern California, from Bakersfield to San Diego.

The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.

The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.