As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Kristi Reynolds is a chronic disease epidemiologist and the director of Epidemiologic Research for the Department of Research & Evaluation. Her research focuses on the prevention and treatment of hypertension, dyslipidemia, diabetes, and cardiovascular disease. She also studies medication adherence, drug safety, and cardiovascular quality of care and outcomes. She has substantial experience leading and collaborating on multisite ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
In December 2021, the Pfizer-BioNTech medication Paxlovid received emergency authorization as a treatment to prevent severe health problems from COVID-19 that could lead to hospitalization and death. But recently, small studies with less than a dozen people began to show up in the media linking the medication to a rebound in COVID-19 symptoms following recovery. ...
A study of patients at Kaiser Permanente in Southern California showed that when both the delta and omicron variants were circulating in December 2021, patients who had SARS-CoV-2 infections with the omicron variant had substantially less risk of severe illness and shorter hospital stays than those infected with the delta variant. The study was published ...
A study published June 6, 2022, in The Joint Commission Journal on Quality and Patient Safety showed that a comprehensive approach to improving colon cancer care at Kaiser Permanente in Southern California resulted in a 24% decrease in mortality over 7 years. “If a new drug or surgical procedure reduced deaths this dramatically, it would ...
A new dedicated clinical research space at the Kaiser Permanente Los Angeles Medical Center provides researchers and staff with expanded opportunities to bring groundbreaking clinical research to Kaiser Permanente Southern California members. Located on the first floor of 1505 N. Edgemont on the medical center campus, the 1,400-square-foot Kaiser Permanente Clinical Research Center at Los ...
William Towner, MD, FACP, FIDSA, is the regional physician director for the Division of Clinical Trials and leads the Clinician Investigator Program for the Southern California Permanente Medical Group. He also serves in a leadership role for HIV services at Kaiser Permanente Southern California. He was extensively involved in research on infectious diseases since 2000 ...
The May issue of IMPACT newsletter includes stories on COVID-19 vaccine protection and the immunocompromised, heart attack incidence after the 2020 U.S. presidential election, a video highlighting cancer clinical trials at Kaiser Permanente Southern California, and a Q&A with Dr. William Towner, regional physician director of Clinical Trials.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.