About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Karen Coleman headshot
Karen J. Coleman, PhD, MS
Research Scientist III
Division of Health Services Research & Implementation Science

Dr. Karen Coleman studies the behavioral, social, and environmental determinants of success after weight loss surgery. An additional focus of her research is on interventions in primary care settings for adult depression. Dr. Coleman’s main areas of interest are health equity and the study of factors at the level of the patient, the provider, and the system that lead to successful interventions for physical and emotional wellness.

Dr. Coleman directs one of the largest weight loss registries ...

Featured Video

Advancing treatments through clinical trials

Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)


Featured Image of News Story Titled: Down syndrome linked to higher risk of severe COVID-19

Down syndrome linked to higher risk of severe COVID-19

Before COVID-19 vaccines became available, people with Down syndrome were less likely to be diagnosed with COVID-19 than people without the condition, according to a study of more than 12,000 Kaiser Permanente Southern California members published on June 24, 2022, in The Journal of Infectious Diseases. However, the study found, people with Down syndrome faced ...

Dr. Anny Xiang honored with prestigious American Diabetes Association award

Anny Xiang, PhD, MS, scientific director of the Division of Biostatics Research at the Department of Research & Evaluation, received the American Diabetes Association’s 2022 Norbert Freinkel Award on June 4, 2022. The lecture award is the ADA’s highest award for outstanding contributions in the field of diabetes and pregnancy. “Dr. Xiang’s body of work ...

COVID-related hospitalizations are rare after Paxlovid treatment

In December 2021, the Pfizer-BioNTech medication Paxlovid received emergency authorization as a treatment to prevent severe health problems from COVID-19 that could lead to hospitalization and death. But recently, small studies with less than a dozen people began to show up in the media linking the medication to a rebound in COVID-19 symptoms following recovery. ...

New approach reduces colon cancer deaths

A study published June 6, 2022,  in The Joint Commission Journal on Quality and Patient Safety showed that a comprehensive approach to improving colon cancer care at Kaiser Permanente in Southern California resulted in a 24% decrease in mortality over 7 years. “If a new drug or surgical procedure reduced deaths this dramatically, it would ...

Clinical research center opens at Los Angeles Medical Center

A new dedicated clinical research space at the Kaiser Permanente Los Angeles Medical Center provides researchers and staff with expanded opportunities to bring groundbreaking clinical research to Kaiser Permanente Southern California members. Located on the first floor of 1505 N. Edgemont on the medical center campus, the 1,400-square-foot Kaiser Permanente Clinical Research Center at Los ...


Featured Division

Biostatistics Research

Our biostatisticians provide expert guidance on working with real-world clinical data to investigators in all of our scientific divisions.

Investigators with the Division of Biostatistics Research collaborate closely with scientists from the department’s other scientific divisions, as well as physician researchers at medical centers across Kaiser Permanente Southern California. They provide expertise and guidance on study design, power and sample size calculations, data management, data analysis and interpretation, and statistical methodology.

Investigators from the division have expertise in study design and data analysis for observational studies and clinical trials to address study questions. Their expertise spans standard and modern methods that deal with complex and big data for population and causal inferences as well as disease prediction.

Each division has at least one dedicated collaborative biostatistician research scientist assigned to provide statistical guidance on its research studies. In addition, one of the collaborative biostatistician researcher scientists leads the Regional Research Statistical Support team, which supports medical center-based researchers.