As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Annette Adams is an injury epidemiologist and a research scientist in the Department of Research & Evaluation. Much of her work to date has focused on injuries in older adults, pharmacologic influences on bone health, the effects of long-term use of bisphosphonates on fracture risk and adverse events, risk factors for falls and fractures, and outcomes of fractures.
Dr. Adams has led multiple projects of various sizes. She was the principal investigator for a large, multisite project ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
In December 2021, the Pfizer-BioNTech medication Paxlovid received emergency authorization as a treatment to prevent severe health problems from COVID-19 that could lead to hospitalization and death. But recently, small studies with less than a dozen people began to show up in the media linking the medication to a rebound in COVID-19 symptoms following recovery. ...
A study of patients at Kaiser Permanente in Southern California showed that when both the delta and omicron variants were circulating in December 2021, patients who had SARS-CoV-2 infections with the omicron variant had substantially less risk of severe illness and shorter hospital stays than those infected with the delta variant. The study was published ...
A study published June 6, 2022, in The Joint Commission Journal on Quality and Patient Safety showed that a comprehensive approach to improving colon cancer care at Kaiser Permanente in Southern California resulted in a 24% decrease in mortality over 7 years. “If a new drug or surgical procedure reduced deaths this dramatically, it would ...
A new dedicated clinical research space at the Kaiser Permanente Los Angeles Medical Center provides researchers and staff with expanded opportunities to bring groundbreaking clinical research to Kaiser Permanente Southern California members. Located on the first floor of 1505 N. Edgemont on the medical center campus, the 1,400-square-foot Kaiser Permanente Clinical Research Center at Los ...
William Towner, MD, FACP, FIDSA, is the regional physician director for the Division of Clinical Trials and leads the Clinician Investigator Program for the Southern California Permanente Medical Group. He also serves in a leadership role for HIV services at Kaiser Permanente Southern California. He was extensively involved in research on infectious diseases since 2000 ...
The May issue of IMPACT newsletter includes stories on COVID-19 vaccine protection and the immunocompromised, heart attack incidence after the 2020 U.S. presidential election, a video highlighting cancer clinical trials at Kaiser Permanente Southern California, and a Q&A with Dr. William Towner, regional physician director of Clinical Trials.
Investigators with the Division of Biostatistics Research collaborate closely with scientists from the department’s other scientific divisions, as well as physician researchers at medical centers across Kaiser Permanente Southern California. They provide expertise and guidance on study design, power and sample size calculations, data management, data analysis and interpretation, and statistical methodology.
Investigators from the division have expertise in study design and data analysis for observational studies and clinical trials to address study questions. Their expertise spans standard and modern methods that deal with complex and big data for population and causal inferences as well as disease prediction.
Each division has at least one dedicated collaborative biostatistician research scientist assigned to provide statistical guidance on its research studies. In addition, one of the collaborative biostatistician researcher scientists leads the Regional Research Statistical Support team, which supports medical center-based researchers.