Rethinking MS treatment: Why less may be more
For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation ...
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Staying active during pregnancy helps keep postpartum weight off
For years, researchers have known that many people struggle to lose the weight they gain during pregnancy. Up to 1 in 4 individuals retain at least 10 pounds 1 to 2 years after giving birth, and this ...
Wildfire smoke studies reveal differing health risks
Wildfire smoke has increasingly been recognized as a serious public health threat. Now, 2 new Kaiser Permanente studies in Southern California have examined how health risks for both young and old people ...
Researcher Dr. Hui Zhou’s joyful New Year’s Day walk
On a rainy New Year’s morning in Pasadena, Dr. Hui Zhou, a research scientist with the Department of Research & Evaluation, walked alongside Kaiser Permanente’s float, “A Better Idea ...
Physicians can influence people to try to lose weight
September 1, 2020People who were overweight were less likely to have tried to lose weight if their primary care provider had not talked with them about weight loss, a Kaiser Permanente study found. “By delivering factual information on weight status, primary care providers may motivate their patients to consider weight management strategies,” said Deborah Rohm Young, PhD, the ...Read more...Atypical femur fractures rise with longer bisphosphonate use
August 20, 2020In a study published in the New England Journal of Medicine, Kaiser Permanente Southern California research scientists report that while atypical femur fracture risk is rare, it does increase with longer use of bisphosphonate to treat osteoporosis, especially after 5 years. Asian women had approximately 5 times the risk of these fractures with prolonged bisphosphonate ...Read more...Obesity increases risk of death from COVID-19, particularly for men and young people
August 14, 2020In a study published in Annals of Internal Medicine, Kaiser Permanente research shows that obesity was associated with a substantial increased risk of death from COVID-19. However, it also found that the risk of death from COVID-19 associated with obesity is not uniform among those who are obese, but instead disproportionately affects men and people ...Read more...Kaiser Permanente joins late-stage COVID-19 vaccine study
August 12, 2020Today, Kaiser Permanente began participating in a phase 3 clinical trial to test an investigational vaccine against SARS-CoV-2, the virus causing the current COVID-19 global pandemic. Kaiser Permanente plans to enroll approximately 1,400 participants at 4 sites in California and Oregon. The goal for this trial is to enroll up to 30,000 participants at more ...Read more...Improving care through research
July 21, 2020The Care Improvement Research Team is a groundbreaking partnership in Kaiser Permanente Southern California, bringing researchers and clinicians together to improve health care quality and affordability for Kaiser Permanente members and people throughout the world. Through CIRT, research scientists team up with frontline clinicians to identify research questions that are important to patients and the doctors ...Read more...Annual report shows Kaiser Permanente Southern California research stretching the frontier of health
July 8, 2020The growing need for solutions to important health questions requires innovative thinking beyond what experts know today. The Department of Research & Evaluation’s 2019 Annual Report, “Stretching the Frontier: Research Improving Health and Well-being,” illustrates some of the innovative ways Kaiser Permanente Southern California researchers and clinicians are working together toward answers to those questions. The ...Read more...Few pregnant women admitted for delivery have COVID-19
July 3, 2020New research shows that few women admitted to Kaiser Permanente Southern California hospitals to give birth this spring tested positive for COVID-19. Those who did were asymptomatic, and none passed on the infection to their newborns. “We had heard from our colleagues in New York about the high rate of COVID-19 among pregnant women coming to ...Read more...Screening cancer patients for distress
June 29, 2020When she was a new scientist at Kaiser Permanente Southern California, Erin E. Hahn, PhD, MPH, had an intense interest in cancer research. Oncologists invited her into their quarterly meetings so she could see and hear the challenges they faced. One of those challenges was depression and anxiety among cancer patients. Dr. Hahn and others worked ...Read more...Patient advisors revolutionize research
June 29, 2020Fifteen years ago when Matt Owen was a freshman psychology major in college, he had a “psychotic break from reality.” “I started having hallucinations that altered my mind in a way that dealing with everyday life became challenging,” he said. “It changed the course of my life.” Times were rocky for a while, including more than a ...Read more...Resident research improves patient care
June 29, 2020At the Kaiser Permanente Los Angeles Medical Center, pediatric resident Jacqueline Nguyen, MD, wanted to know how flu shots affected young patients with asthma. With help from her resident research advisor, she dug into data from electronic health records and found that flu vaccination reduced hospitalization rates for respiratory issues by 25% over the 6-year ...Read more...