Kidney Diseases studies
Archimedes IndiGO End-Stage Renal Disease Tool Development and Validation
Archimedes IndiGO will be used to predict outcomes for Chronic Kidney Disease and provide an interface for patient management. The accuracy of outcomes prediction will be tested in this study.
Development of a CKD Discordance Index to Identify High Healthcare Utilization
The goals of this pilot project are to develop a chronic kidney disease (CKD) discordance index defined by the presence of chronic conditions and treatments that oppose, contradict, or complicate CKD treatment or worsen kidney function in a subsample of CKD patients from KPSC
Disparities in Progression to Renal Replacement Therapy
This retrospective cohort study will explore the reasons for the increased incidence of end-stage renal disease in African Americans and Hispanics by focusing on quality of care for diabetes, hypertension, and chronic kidney disease.
Electronic Clinical Surveillance to Measure and Improve Safety in Ambulatory Care
This study seeks to determine the incidence of three types of medical errors and the underlying factors that contribute to them within the ambulatory care settings of a large, diverse integrated delivery system. Specifically, we are studying delayed diagnosis of kidney disease (diagnostic error), use of contraindicated medications among patients with a history of falls (treatment error), and lack of annual monitoring for patients on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (preventive error).
Principal Investigator:Kim N. Danforth, ScD, MPH
Funding Source:Agency for Healthcare Research and Quality (AHRQ)
Funding Years:2015 - 2018
Research Categories:Kidney Diseases
Kidney Function Decline in Patients with CKD and Untreated Hepatitis C Infection
Studies evaluating the role of hepatitis C viral (HCV) infection on the progression of CKD are few and conflicting. Therefore, we evaluated the association of untreated HCV on kidney function decline in patients with stage 3-5 CKD.
Population-based diabetes in youth registry: SEARCH for Diabetes in Youth, Phase 4, California Site
The aims of this study are (1) to ascertain prevalent diabetes cases in calendar year 2017 among youth age <20 years at diagnosis, using cost-efficient approaches that maximize use of information in the electronic health records (EHRs) and administrative databases, (2) to continue to ascertain newly diagnosed (incident 2015-2020) diabetes cases in youth age <20 years, using cost-efficient approaches that maximize use of EHRs and administrative databases, (3) to determine agreement between the etiological classification of diabetes type using biochemical markers and provider assessment; to describe selected clinical characteristics at diagnosis, and to establish an infrastructure that facilitates the development of more detailed ancillary studies by storing biological samples and preserving contact with potential study participants, and (4) To optimize efficiency of SEARCH surveillance activities through targeted Development and Validation (D&V) Projects designed to utilize electronic health data to operationalize each of the three tiers of surveillance to the extent possible. (1U18 DP006133)