Health Economics studies
Developing a Risk Prediction Model and Evaluating the Economic Burden of Ankylosing Spondylitis in an Integrated Healthcare System
The primary aim is to develop an ankylosing spondylitis risk prediction model using data from Kaiser’s electronic medical records (EMR). We will also evaluate medical expenditure, health related quality of life and work productivity losses associated with ankylosing spondylitis.
Economic, Epidemiologic and Clinical Burden Associated with Neutropenia and Febrile Neutropenia in Three Cancers
The primary objective of this study is to estimate the resource utilization and direct medical expenditure associated with neutropenia and febrile neutropenia, in Non-Hodgkin’s Lymphoma, Breast cancer and Lung cancer patients. The secondary objective is to determine the trend of incidence of neutropenia with and without fever in Non-Hodgkin’s Lymphoma, Breast cancer and Lung cancer. The study will also describe management patterns and evaluate trend of management patterns for febrile neutropenia. Lastly, we will also estimate the febrile neutropenia specific mortality rate in hospitalized patients by cancer type.
Medical Expenditure Panel Survey (MEPS)
The aim of this study is to verify the cost of care for persons with multiple sclerosis.
Patterns and Predictors of Transitions in Adult Attention-Deficit Hyperactivity Disorder
This study will estimate the epidemiologic and economic outcomes associated with the adult attention deficit hyperactivity disorder (ADHD). We also assess characteristics, predictors, and time frame for patients who transition to more complex ADHD within the inception cohort and generate prediction models for transition. The study also examines treatment patterns, medication adherence and healthcare utilization patterns of the inception cohort.
Real World Effectiveness and Economic Impact of Subcutaneous Methotrexate compared to Oral Methotrexate Treatment for Rheumatoid Arthritis
This prospective study will evaluate the real-world effectiveness of subcutaneous vs. oral methotrexate treatment on disease activity and functional status of rheumatoid arthritis patients. We will also evaluate effectiveness on patient centered outcomes, treatment adherence, cost, and work productivity. Lastly, using a discrete choice experiment, we will estimate patient’s valuation of these outcomes and their willingness to pay.
Total Direct Medical Expenditure Associated with Transition to Diverticulitis
This study will estimate the economic, clinical and epidemiologic outcomes associated with the transition from diverticulosis to diverticulitis. We further assess these outcomes associated with recurrence of diverticulitis and also investigate mortality risk due to the disease and during surgical treatments. The study also examines the socio-demographic and other factors associated with diverticulitis and its recurrence; barrier’s to surgical treatment alternatives and associated utilization; other treatment options for this disease.