Neurological Disorders studies
ASCEND Clinical Trial
A clinical trial to study the efficacy of natalizumab on reducing disability progression in subjects with secondary progressive multiple sclerosis.
Principal Investigator:
Annette M. Langer-Gould, MD, PhD, MSFunding Source:
Biogen Idec, Inc.Funding Years:
2011 - 2016Assessing the association between RZV and reduced risk of dementia
This is a retrospective matched cohort study to evaluate the association between two doses of the recombinant zoster vaccine and dementia, Alzheimer’s disease, and mild cognitive impairment among Southern California adults>=65 years.
Principal Investigator:
Hung Fu Tseng, PhD, MPHFunding Source:
GlaxoSmithKline, LLCFunding Years:
2023 - 2026Cholesterol-lowering medication as risk factors for amyotrophic lateral sclerosis
The primary objective of this study is to investigate whether the use of cholesterol-lowering medications increases the risk of developing ALS or influences the rate of disease progression among individuals who have ALS.
Principal Investigator:
Annette M. Langer-Gould, MD, PhD, MSFunding Source:
Centers for Disease Control and Prevention (CDC)Funding Years:
2012 - 2013Medical Expenditure Panel Survey (MEPS)
The aim of this study is to verify the cost of care for persons with multiple sclerosis.
Principal Investigator:
Annette M. Langer-Gould, MD, PhD, MSFunding Source:
National Multiple Sclerosis Society (NMSS)Funding Years:
2013Multiple sclerosis clinical care physician fellowship program
Training and mentoring of resident in treatment of multiple sclerosis.
Principal Investigator:
Annette M. Langer-Gould, MD, PhD, MSFunding Source:
National Multiple Sclerosis Society (NMSS)Funding Years:
2013 - 2014Research Categories:
Neurological DisordersSEARCH for Diabetes in Youth Cohort (Follow-Up) Study
Site Principal Investigator:
Jean M. Lawrence, ScD, MPH, MSSAFunding Source:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Funding Years:
2015 - 2020Research Categories:
Cardiovascular Disease, Child and Adolescent Health, Diabetes, Eye Research, Neurological DisordersZoster Vaccine and Risk Factors of Zoster and Post-Herpetic Neuralgia
The aims of the study are to determine the incidence of reactivation of Oka strain VZV in community-dwelling persons vaccinated with zoster vaccines; to test clinical isolates for evidence of recombination between vaccine and wild-type strains VZV; to identify risk factors of HZ among individuals vaccinated with zoster vaccines; to identify risk factors for post-herpetic neuralgia (PHN) among HZ cases who were either vaccinated or unvaccinated with zoster vaccines, and to compare the clinical manifestations and risk of PHN between vaccinated and unvaccinated individuals.