Patient-Reported Outcomes studies

Our researchers use validated survey instruments to learn more from patients related to their feelings about and ability to function with their specific health condition. The primary goal of this research is to increase and improve communication between patients and caregivers, and to help them make better informed health care decisions.

“Project ACHIEVE" (Achieving Patient-Centered Care and Optimized Health In Care Transitions by Evaluating the Value of Evidence)

The overall aims of this project are to identify which transitional care services and outcomes matter most to patients and caregivers, evaluate the comparative effectiveness of ongoing multi-component efforts at improving care transitions, and develop recommendations on best practices for the design, implementation and large-scale national spread of highly effective, patient-centered care transition programs.

Principal Investigator:

Huong Q. Nguyen, PhD, RN

Funding Source:

Patient-Centered Outcomes Research Institute (PCORI)

Funding Years:

2015 - 2019

A Non-Inferiority Comparative Effectiveness Trial of Home-Based Palliative Care in Older Adults (HomePal)

The aim of this pragmatic trial is to compare the effects of a standard home-based palliative care (HBPC) model to a more efficient tech-supported model that includes remote physician supervision/consultation on patient symptom burden and days spent at home in the last 6 months of life and family caregiving preparedness.

Principal Investigator:

Huong Q. Nguyen, PhD, RN

Funding Source:

Patient-Centered Outcomes Research Institute (PCORI)

Funding Years:

2018 - 2022

A Registry to Improve Care and Research in Lung Cancer Screening

This is an award to demonstrate the feasibility of developing a registry of individuals who undergo lung cancer screening with low-dose CT.

Principal Investigator:

Michael K. Gould, MD, MS

Funding Source:

Cancer Research Network (CRN)

Funding Years:

2014 - 2016

Mental Health Research Network II

We have established a Mental Health Research Network including 13 established public-domain research centers based in integrated not-for-profit health systems. These systems provide care to a diverse population of 10 million people in 11 states, and they share rich and compatible data resources to support a range of effectiveness research. Diversity of member demographics, insurance coverage, and organization of health services make this network an ideal environment for studying variation in care, comparing effectiveness and cost of treatments across practice environments, and studying dissemination and health policies. Participating research centers are experienced in a wide range of clinical areas and research methods. The long-term objectives are to expand the Mental Health Research Network to include additional health systems and external investigators, to conduct multi-site observational and experimental studies of comparative effectiveness, to develop and evaluate methods for dissemination and implementation, and to become a national resource of research methods and effectiveness evidence for researchers, patients, providers and healthcare leaders.

Site Principal Investigator:

Karen J. Coleman, PhD, MS

Funding Source:

National Institute of Mental Health (NIMH)

Funding Years:

2014 - 2019

PCORnet Bariatric Study

This study is designed to address the following aims in over 30 clinical sites participating in the national Patient-Centered Outcomes Research Network (PCORnet) Bariatric Study: Aim 1: To what extent does weight loss and weight regain differ across bariatric surgical procedures (Roux-en-Y gastric bypass, sleeve gastrectomy, and adjustable gastric banding) at 1, 3, and 5 years? Aim 2: To what extent does bariatric surgery lead to improvements in diabetes risk at 1, 3, and 5 years? Aim 3: What is the frequency of adverse events following different bariatric surgical procedures at 1, 3, and 5 years? Aim 4: To elicit patient preferences around the risks and benefits regarding the choice of (a) whether to undergo bariatric surgery; (b) which bariatric procedure to utilize; and (c) follow-up care after bariatric surgery.

Site Principal Investigator:

Karen J. Coleman, PhD, MS

Funding Source:

Patient-Centered Outcomes Research Institute (PCORI)

Funding Years:

2016 - 2018

Sleep Disturbance, Inflammation & Cellular Aging in Breast Cancer Survivors (STRIVE 2)

The goal of this prospective recruitment study is to evaluate longitudinal differences in the rates of change in inflammation and telomere erosion in breast cancer survivors vs. non-cancer comparison women to determine if such molecular changes are due to cancer biology, or its treatment, or consequences of aging.

Principal Investigator:

Reina Haque, PhD, MPH

Funding Source:

National Cancer Institute (NCI)

Funding Years:

2016

Sleep Inflammation and Depression Occurrence in Breast Cancer Survivors (STRIVE1)

The aim of this prospective study is to examine the association between sleep disturbance, cellular and genomic markers of inflammation, and depression occurrence in breast cancer survivors.

Site Principal Investigator:

Reina Haque, PhD, MPH

Funding Source:

National Cancer Institute (NCI)

Funding Years:

2012