As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Navdeep Sangha is a vascular neurologist and co-assistant chief of Neurology at the Kaiser Permanente Los Angeles Medical Center. He is the director of the Kaiser Permanente Southern California Tele-Stroke Program and the regional stroke lead for the Southern California Permanente Medical Group.
Dr. Sangha is a principal investigator for stroke clinical trials at the Los Angeles Medical Center, and strives to increase stroke prevention and treatment trial access to patients throughout ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
A new study led by Kaiser Permanente researchers compared how well 4 different types of glucose-lowering medications reduced the risk of heart attack and stroke for patients with type 2 diabetes, providing important new information for these patients and their physicians. The study, published in JAMA Network Open in October, 2025, analyzed data collected on ...
Breast cancer survivors face a high risk of major depressive disorder, also known as clinical depression, particularly if they also have insomnia, according to findings from a new study of Kaiser Permanente members. “We determined that the risk of major depression disorder was markedly higher in breast cancer survivors than in a matched group of ...
Nearly 1 in 5 urinary tract infections (UTIs) in Southern California could be due to E. coli strains transmitted through contaminated meat, according to a new study of Kaiser Permanente Southern California members. The research also found that those living in low-income neighborhoods were at increased risk of these infections. The study was published in ...
After COVID-19 hit in 2020, some physicians within Kaiser Permanente grew concerned that their patients with diabetes weren’t achieving healthy blood sugar control. Even when they came into the office for a visit, follow-up for getting labs to check on their hemoglobin A1c— a blood test that measures the average blood sugar level over the ...
Adolescent and young adult cancer survivors face significantly higher risks of developing chronic medical conditions compared to their peers without cancer, a new study showed. The findings were published in Cancer, the journal of the American Cancer Society. “As cancer survival rates improve for adolescent and young adult cancer survivors, their numbers are increasing,” said ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.