About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Nigel Gupta headshot
Nigel Gupta, MD
Principal Investigator
Los Angeles
Cardiac Electrophysiology
Clinical.Trials@kp.org

Dr. Nigel Gupta is a cardiologist and electrophysiologist and a principal investigator for clinical trials at the Kaiser Permanente Los Angeles Medical Center. His clinical trials participation includes a worldwide trial to evaluate the safety and effectiveness of a left atrial appendage closure device for patients with atrial fibrillation and a trial evaluating the safety and performance of ventricular defibrillation leads. Dr. Gupta is also an investigator in the federally funded National Cardiovascular ...

Featured Video

Research showing value of exercise before COVID-19 diagnosis earns special recognition

Being active can lower your risk of getting seriously ill with COVID, regardless of your race or the chronic conditions you may have, according to research published last year in the American Journal of Preventive Medicine.

The Kaiser Permanente Southern California findings were important, impactful, and influential. As a result, the journal editors chose the research article, “Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups,” as the American Journal of Preventive Medicine 2023 Article of the Year.

News

Featured Image of News Story Titled: More than just a pretty space: What research tells us about parks

More than just a pretty space: What research tells us about parks

For many people, public parks are just a beautiful green space they drive by on their way to work. However, research has shown that parks play a crucial role in people’s physical activity, and the community’s health. By studying parks, researchers aim to understand how these public spaces enhance community health, encourage active lifestyles, and ...

Five questions for Dr. Mingsum Lee

Mingsum Lee, MD, PhD, has been named as the 2025 Southern California Permanente Medical Group Physician Researcher of the Year. Commenting about her selection for the award, one nominator said Dr. Lee “is a true quadruple threat as an exceptional clinician, educator, administrator, and prolific researcher, but also has a humility and generosity which defines ...

Los Angeles wildfires increased virtual medical visits

In January 2025, when wildfires swept from the foothills above Los Angeles into the densely populated urban areas below, evacuations ensued and a thick layer of smoke spread across the region. Air quality plummeted. The number of virtual visits soared and in-person visits also increased. Research led by Kaiser Permanente Southern California and the University ...

Predicting heart issues among breast cancer survivors

Researchers have developed a new risk calculation model to help predict the risks of heart problems for breast cancer survivors. Their research was published in JAMA Oncology in October 2025. “There is limited information about how breast cancer treatments can affect the development of cardiovascular disease,” said study co-senior author Reina Haque, PhD, MPH, a ...

Diabetes medications vary in ability to reduce heart attacks and strokes

A new study led by Kaiser Permanente researchers compared how well 4 different types of glucose-lowering medications reduced the risk of heart attack and stroke for patients with type 2 diabetes, providing important new information for these patients and their physicians. The study, published in JAMA Network Open in October, 2025, analyzed data collected on ...

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Featured Division

Clinician Research

The Division of Clinician Research provides support and resources for researchers who maintain clinical practices while building their own research portfolios.

The Division of Clinician Research provides support and resources for researchers who maintain clinical practices while building their own research portfolios. Key goals include fostering collaboration among clinician researchers, expanding research education, and promoting research that has the potential to transform care and improve the health of our communities.

The division, which was established in 2023, provides administrative support to the Regional Research Committee and the Clinician Investigator Program and manages a team of biostatisticians dedicated to physician research. It co-leads the Care Improvement Research Team, a group that brings together clinicians and research scientists to answer questions with the potential to change practice.

The division actively engages with various collaborators throughout the organization and is working to establish an interconnected network of clinicians, scientists, educators, administrators, and leaders who will work together to drive clinically impactful change through research.