About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Amandeep Sahota, MD
Principal Investigator
Los Angeles Medical Center

Dr. Amandeep Sahota is physician in charge for the Department of Hepatology at the Kaiser Permanente Los Angeles Medical Center. She is also assistant medical director of Transplant Services for Kaiser Permanente Southern California. In this role, she promotes clinical quality programs, implementation of virtual medicine, and data analytics on chronic diseases outcomes. Her efforts have improved patient access to care, advanced screening for advanced liver disease, and innovated care delivery ...

Featured Video

Advancing treatments through clinical trials

Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)


Featured Image of News Story Titled: 5 questions for …  Dr. William Towner

5 questions for … Dr. William Towner

William Towner, MD, FACP, FIDSA, is the regional physician director for the Division of Clinical Trials and leads the Clinician Investigator Program for the Southern California Permanente Medical Group. He also serves in a leadership role for HIV services at Kaiser Permanente Southern California. He was extensively involved in research on infectious diseases since 2000 ...

COVID-19 vaccine protection against hospitalization wanes

Research released in The Lancet Respiratory Medicine shows that a booster dose of the Pfizer COVID-19 vaccine provides strong protection, roughly 80% in the first few months against hospital admissions and emergency department visits caused by the delta and omicron variants. However, against omicron, this protection wanes over time for immunocompromised individuals — even after ...

Heart attacks increased in days after 2020 election

A Kaiser Permanente study conducted in Southern and Northern California found hospitalizations for heart attack, stroke, and heart failure were 17% higher in the 5 days after the 2020 election than in the same 5 days 2 weeks before the election. The study was published April 20, 2022, in JAMA Network Open. “This study of ...

Shoulder pain rare after vaccination

Shoulder pain and injury are extremely rare after any type of vaccination in the upper arm, according to pre-pandemic Kaiser Permanente research published March 22, 2022, in Annals of Internal Medicine. Conducted from April 2016 through December 2017, the study found fewer than 1 in 10,000 people reported shoulder injuries in the more than 2.2 ...

3 doses of Moderna COVID-19 vaccine highly effective against hospitalization from omicron or delta.

Kaiser Permanente research published Feb. 21, 2022, in Nature Medicine shows that while Moderna COVID-19 vaccine protection is strong against coronavirus infection by the delta variant, it is not as strong against infection from the omicron variant. Three doses of the Moderna COVID-19 vaccine were highly effective against hospitalization caused by infection from either the ...


Featured Division

Clinical Trials Research

Our physician investigators conduct clinical trials in communities across Southern California, from Bakersfield to San Diego.

The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.

The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.