As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Nigel Gupta is a cardiologist and electrophysiologist and a principal investigator for clinical trials at the Kaiser Permanente Los Angeles Medical Center. His clinical trials participation includes a worldwide trial to evaluate the safety and effectiveness of a left atrial appendage closure device for patients with atrial fibrillation and a trial evaluating the safety and performance of ventricular defibrillation leads. Dr. Gupta is also an investigator in the federally funded National Cardiovascular ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation with MS. However, new research from Kaiser Permanente ...
For years, researchers have known that many people struggle to lose the weight they gain during pregnancy. Up to 1 in 4 individuals retain at least 10 pounds 1 to 2 years after giving birth, and this lingering weight can raise their long‑term risk of hypertension, cardiovascular disease, and other metabolic problems. Despite the importance ...
Wildfire smoke has increasingly been recognized as a serious public health threat. Now, 2 new Kaiser Permanente studies in Southern California have examined how health risks for both young and old people might be associated with exposure. One study showed that long-term exposure increased the risk of death among older adults, while another found that ...
On a rainy New Year’s morning in Pasadena, Dr. Hui Zhou, a research scientist with the Department of Research & Evaluation, walked alongside Kaiser Permanente’s float, “A Better Idea for Health Care,” in the Rose Parade. It was a moment of pride and joy. Dr. Zhou wasn’t just proud to represent Kaiser Permanente. … ...
For many people, public parks are just a beautiful green space they drive by on their way to work. However, research has shown that parks play a crucial role in people’s physical activity, and the community’s health. By studying parks, researchers aim to understand how these public spaces enhance community health, encourage active lifestyles, and ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
Investigators with the Division of Health Services Research & Implementation Science study how care is delivered, identify opportunities for care improvement, and implement new approaches for organizing and delivering health services. The division brings together scientists with diverse expertise and training, including emergency medicine, epidemiology, health services research, implementation science, internal medicine, nursing, pharmaceutical economics, and pulmonology.
The division co-leads the Care Improvement Research Team, a research team embedded within Kaiser Permanente Southern California’s quality improvement ecosystem. The team works closely with clinical and operational partners at Kaiser Permanente Southern California to identify, prioritize, and solve problems related to quality and affordability. Its goal is to reduce unnecessary practice variation, improve affordability, and transform care.