As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Jeff Slezak is a collaborative biostatistician research scientist for the Division of Epidemiologic Research in the Department of Research & Evaluation. He is focused on the application of statistics to improve knowledge and patient care. He is interested in predictive modeling and in identifying high-risk populations. He has over 20 years of experience as a statistician and has collaborated with many researchers.
Jeff has primarily focused on studies of prostate and bladder cancer ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
Hui Zhou PhD, MS, is the biostatistician lead in the Division of Epidemiologic Research for the Department of Research & Evaluation. There she collaborates with epidemiologists and clinical investigators on research studies ranging from conditions like hypertension, diabetes, chronic kidney disease, cardiovascular disease, and bone fractures. Dr. Zhou has extensive research experience in prediction model ...
A Kaiser Permanente study found that the PREVENT cardiovascular risk equation had strong overall ability to predict 10-year cardiovascular disease risk in Asian, Native Hawaiian, and Other Pacific Islander adults. However, its accuracy differed across specific Asian ethnic subgroups and showed consistent patterns of over- and under-estimating when grouping by race and ethnicity. The study ...
For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation with MS. However, new research from Kaiser Permanente ...
For years, researchers have known that many people struggle to lose the weight they gain during pregnancy. Up to 1 in 4 individuals retain at least 10 pounds 1 to 2 years after giving birth, and this lingering weight can raise their long‑term risk of hypertension, cardiovascular disease, and other metabolic problems. Despite the importance ...
Wildfire smoke has increasingly been recognized as a serious public health threat. Now, 2 new Kaiser Permanente studies in Southern California have examined how health risks for both young and old people might be associated with exposure. One study showed that long-term exposure increased the risk of death among older adults, while another found that ...
The latest IMPACT newsletter highlights Kaiser Permanente research and its real-world relevance. This issue explores why less frequent MS treatment may be just as effective, how staying active during pregnancy supports a healthier postpartum weight, and what new studies reveal about wildfire smoke risks. You’ll also find research on heart disease risk prediction across Asian ethnicities and a Q&A with Dr. Hui Zhou, reflecting on science, service, and being mom to this year’s Rose Queen.
The Division of Clinician Research provides support and resources for researchers who maintain clinical practices while building their own research portfolios. Key goals include fostering collaboration among clinician researchers, expanding research education, and promoting research that has the potential to transform care and improve the health of our communities.
The division, which was established in 2023, provides administrative support to the Regional Research Committee and the Clinician Investigator Program and manages a team of biostatisticians dedicated to physician research. It co-leads the Care Improvement Research Team, a group that brings together clinicians and research scientists to answer questions with the potential to change practice.
The division actively engages with various collaborators throughout the organization and is working to establish an interconnected network of clinicians, scientists, educators, administrators, and leaders who will work together to drive clinically impactful change through research.