As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Brian S. Mittman is a research scientist in the Department of Research & Evaluation with additional affiliations at the University of Southern California and the University of California, Los Angeles, where he co-leads the UCLA Clinical and Translational Science Institute’s Dissemination, Implementation and Improvement Science Initiative.
Dr. Mittman chaired the planning committee that launched the journal Implementation Science and served as co-editor in chief from ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
A new study led by Kaiser Permanente researchers compared how well 4 different types of glucose-lowering medications reduced the risk of heart attack and stroke for patients with type 2 diabetes, providing important new information for these patients and their physicians. The study, published in JAMA Network Open in October, 2025, analyzed data collected on ...
Breast cancer survivors face a high risk of major depressive disorder, also known as clinical depression, particularly if they also have insomnia, according to findings from a new study of Kaiser Permanente members. “We determined that the risk of major depression disorder was markedly higher in breast cancer survivors than in a matched group of ...
Nearly 1 in 5 urinary tract infections (UTIs) in Southern California could be due to E. coli strains transmitted through contaminated meat, according to a new study of Kaiser Permanente Southern California members. The research also found that those living in low-income neighborhoods were at increased risk of these infections. The study was published in ...
After COVID-19 hit in 2020, some physicians within Kaiser Permanente grew concerned that their patients with diabetes weren’t achieving healthy blood sugar control. Even when they came into the office for a visit, follow-up for getting labs to check on their hemoglobin A1c— a blood test that measures the average blood sugar level over the ...
Adolescent and young adult cancer survivors face significantly higher risks of developing chronic medical conditions compared to their peers without cancer, a new study showed. The findings were published in Cancer, the journal of the American Cancer Society. “As cancer survival rates improve for adolescent and young adult cancer survivors, their numbers are increasing,” said ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
Investigators with the Division of Biostatistics Research collaborate closely with scientists from the department’s other scientific divisions, as well as physician researchers at medical centers across Kaiser Permanente Southern California. They provide expertise and guidance on study design, power and sample size calculations, data management, data analysis and interpretation, and statistical methodology.
Investigators from the division have expertise in study design and data analysis for observational studies and clinical trials to address study questions. Their expertise spans standard and modern methods that deal with complex and big data for population and causal inferences as well as disease prediction.
Each division has at least one dedicated collaborative biostatistician research scientist assigned to provide statistical guidance on its research studies. In addition, one of the collaborative biostatistician researcher scientists leads the Regional Research Statistical Support team, which supports medical center-based researchers.