About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Michael Girvigian headshot
Michael R. Girvigian, MD
Principal Investigator
Los Angeles Medical Center

Dr. Michael Girvigian is a radiation oncologist, assistant chief of the Department of Radiation Oncology, and co-director of the image-guided radiosurgery program for the Kaiser Permanente Los Angeles Medical Center and the Southern California Permanente Medical Group. His clinical focus is on the management of benign and malignant tumors of the brain and spine with the use of image-guided radiosurgery and radiotherapy. He also introduced the use of stereotactic body radiotherapy in the organization ...


Featured Image of News Story Titled: Exploring links between childhood maltreatment, epigenetics, and mental health

Exploring links between childhood maltreatment, epigenetics, and mental health

Researchers at Kaiser Permanente Southern California and the University of Southern California are teaming up on a new research project to better understand the relationship between child maltreatment, epigenetics, and mental health. Sonya Negriff, PhD, a developmental psychologist with Kaiser Permanente Southern California’s Department of Research & Evaluation, will lead the study along with Ferol ...

Better screening for latent tuberculosis

Investigators in Kaiser Permanente Southern California and Kaiser Permanente Northern California have kicked off a new research project to develop better screening for latent tuberculosis. The project, led by Sara Tartof, PhD, MPH, an infectious disease epidemiologist with the Southern California Department of Research & Evaluation, is funded by the National Institute of Allergy and ...

Launching a multisite clinical trial in the midst of a pandemic

In early March 2020, as it became clear the novel coronavirus was closing in on Southern California, clinical trials leaders from the Department of Research & Evaluation began assessing options for an investigational treatment that could be studied through clinical trials. With no approved medications to fight COVID-19, the need for an investigational option to ...

Advancing treatments through clinical trials

Kaiser Permanente’s clinical trials program helps advance treatment for health conditions ranging from heart disease and cancer to infectious diseases, such as HIV and COVID-19. William Towner, MD, FACP, FIDSA, physician director for clinical trials at Kaiser Permanente Southern California, has seen firsthand how clinical trials can contribute to the development of more effective and ...

5 questions for … Dr. Deborah Cohen

Deborah A. Cohen, MD, MPH, an international expert on the health benefit of parks, is the newest scientist at the Department of Research & Evaluation. She began working in the department’s Division of Behavioral Research in January. She previously worked as a senior physician policy researcher at the RAND Corporation. She has served on panels ...


Featured Division

Clinical Trials Research

Our physician investigators conduct clinical trials in communities across Southern California, from Bakersfield to San Diego.

The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.

The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.