As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Karen Coleman studies the behavioral, social, and environmental determinants of success after weight loss surgery. An additional focus of her research is on interventions in primary care settings for adult depression. Dr. Coleman’s main areas of interest are health equity and the study of factors at the level of the patient, the provider, and the system that lead to successful interventions for physical and emotional wellness.
Dr. Coleman directs one of the largest weight loss registries ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
In January 2025, when wildfires swept from the foothills above Los Angeles into the densely populated urban areas below, evacuations ensued and a thick layer of smoke spread across the region. Air quality plummeted. The number of virtual visits soared and in person visits also increased. Research led by Kaiser Permanente Southern California and the ...
Researchers have developed a new risk calculation model to help predict the risks of heart problems for breast cancer survivors. Their research was published in JAMA Oncology in October 2025. “There is limited information about how breast cancer treatments can affect the development of cardiovascular disease,” said study co-senior author Reina Haque, PhD, MPH, a ...
A new study led by Kaiser Permanente researchers compared how well 4 different types of glucose-lowering medications reduced the risk of heart attack and stroke for patients with type 2 diabetes, providing important new information for these patients and their physicians. The study, published in JAMA Network Open in October, 2025, analyzed data collected on ...
Breast cancer survivors face a high risk of major depressive disorder, also known as clinical depression, particularly if they also have insomnia, according to findings from a new study of Kaiser Permanente members. “We determined that the risk of major depression disorder was markedly higher in breast cancer survivors than in a matched group of ...
Nearly 1 in 5 urinary tract infections (UTIs) in Southern California could be due to E. coli strains transmitted through contaminated meat, according to a new study of Kaiser Permanente Southern California members. The research also found that those living in low-income neighborhoods were at increased risk of these infections. The study was published in ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
Investigators with the Division of Epidemiologic Research apply rigorous research methods to address important health questions that have the potential to change clinical practice and health care delivery. The division’s research portfolio spans the care continuum, from etiology and prevention to survivorship and quality of life.
Division investigators have expertise in traditional epidemiologic studies, post-marketing safety and effectiveness studies, and outcomes research. Current research areas include cancer, cardiovascular disease, COVID-19, diabetes, infectious disease, molecular epidemiology, orthopedics and bone health, perinatal health, pharmacoepidemiology, and vaccines.