As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Ahmed Dehal is a board-certified general surgeon with a second board certification in complex surgical oncology at the Kaiser Permanente Panorama City Medical Center. He serves as area research chair for Panorama City on the Southern California Permanente Medical Group Regional Research Committee. He is an associate professor in Clinical Science at the Kaiser Permanente Bernard J. Tyson School of Medicine. Dr. Dehal has published more than 40 articles in peer-reviewed journals as well as multiple ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
Restaurants in the United States are known for generous portions, often serving far more food than most adults need in a single meal. Those oversized portions have long been linked to overeating and, over time, to higher rates of obesity and chronic disease. A new study conducted in real restaurants suggests there may be a ...
While the typical assumption would be that it takes a major academic campus to foster medical innovation, Kaiser Permanente is proving that wrong. The Kaiser Permanente Riverside Medical Center has become a hub for clinical trial innovation under the direction of Vivienne Hau, MD, PhD, a medical and surgical vitreoretinal specialist who has built a ...
Hui Zhou PhD, MS, is the biostatistician lead in the Division of Epidemiologic Research for the Department of Research & Evaluation. There she collaborates with epidemiologists and clinical investigators on research studies ranging from conditions like hypertension, diabetes, chronic kidney disease, cardiovascular disease, and bone fractures. Dr. Zhou has extensive research experience in prediction model ...
A Kaiser Permanente study found that the PREVENT cardiovascular risk equation had strong overall ability to predict 10-year cardiovascular disease risk in Asian, Native Hawaiian, and Other Pacific Islander adults. However, its accuracy differed across specific Asian ethnic subgroups and showed consistent patterns of over- and under-estimating when grouping by race and ethnicity. The study ...
For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation with MS. However, new research from Kaiser Permanente ...
The latest IMPACT newsletter highlights Kaiser Permanente research and its real-world relevance. This issue explores why less frequent MS treatment may be just as effective, how staying active during pregnancy supports a healthier postpartum weight, and what new studies reveal about wildfire smoke risks. You’ll also find research on heart disease risk prediction across Asian ethnicities and a Q&A with Dr. Hui Zhou, reflecting on science, service, and being mom to this year’s Rose Queen.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.