About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Yvonne Tsai, MD Clinician Investigator
Yvonne S. Tsai, MD
Clinician Investigator

Pediatrics
Orange County

Dr. Yvonne Tsai is a general pediatrician at the Kaiser Permanente Barranca Medical Office in Orange County.  She is a fellow of the American Academy of Pediatrics and has an interest in conducting translational research to better understand populations and disease trends that may be used to support evidence-based health care planning.

Dr Tsai is a member of the Kaiser Permanente Virtual Medical Center Team. She has a particular interest in clinical data science, as it may be applied to ...

Featured Video

Advancing treatments through clinical trials

Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)

News

Featured Image of News Story Titled: When more isn’t more: Smaller restaurant portions left diners just as full

When more isn’t more: Smaller restaurant portions left diners just as full

Restaurants in the United States are known for generous portions, often serving far more food than most adults need in a single meal. Those oversized portions have long been linked to overeating and, over time, to higher rates of obesity and chronic disease. A new study conducted in real restaurants suggests there may be a ...

Transforming sight through clinical trials

While the typical assumption would be that it takes a major academic campus to foster medical innovation, Kaiser Permanente is proving that wrong. The Kaiser Permanente Riverside Medical Center has become a hub for clinical trial innovation under the direction of Vivienne Hau, MD, PhD, a medical and surgical vitreoretinal specialist who has built a ...

5 questions for Dr. Hui Zhou

Hui Zhou PhD, MS, is the biostatistician lead in the Division of Epidemiologic Research for the Department of Research & Evaluation. There she collaborates with epidemiologists and clinical investigators on research studies ranging from conditions like hypertension, diabetes, chronic kidney disease, cardiovascular disease, and bone fractures. Dr. Zhou has extensive research experience in prediction model ...

Study evaluates heart disease risk prediction across Asian ethnicities

A Kaiser Permanente study found that the PREVENT cardiovascular risk equation had strong overall ability to predict 10-year cardiovascular disease risk in Asian, Native Hawaiian, and Other Pacific Islander adults. However, its accuracy differed across specific Asian ethnic subgroups and showed consistent patterns of over- and under-estimating when grouping by race and ethnicity. The study ...

Rethinking MS treatment: Why less may be more

For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation with MS. However, new research from Kaiser Permanente ...

Events

Featured Division

Health Services Research & Implementation Science

Our health services researchers bring together scientific and clinical expertise to find better ways to improve care.

Investigators with the Division of Health Services Research & Implementation Science study how care is delivered, identify opportunities for care improvement, and implement new approaches for organizing and delivering health services. The division brings together scientists with diverse expertise and training, including emergency medicine, epidemiology, health services research, implementation science, internal medicine, nursing, pharmaceutical economics, and pulmonology.

The division co-leads the Care Improvement Research Team, a research team embedded within Kaiser Permanente Southern California’s quality improvement ecosystem. The team works closely with clinical and operational partners at Kaiser Permanente Southern California to identify, prioritize, and solve problems related to quality and affordability. Its goal is to reduce unnecessary practice variation, improve affordability, and transform care.