As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Kimberly Ferrante is an obstetrics-gynecology physician in the urogynecology division at the Kaiser Permanente San Diego Medical Center. She began her 2-year appointment in the Southern California Permanente Medical Group Clinical Investigator Program in 2019.
Dr. Ferrante has been actively involved in research since her undergraduate studies in neuroscience. She served as a clinical research coordinator in the area of amyotrophic lateral sclerosis (ALS) and Huntington’s disease. ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
Heidi Brown, MD, MAS, is a urogynecologist and a dissemination and implementation scientist who joined the Department of Research & Evaluation in August 2023. Her research focuses on improving access to effective solutions for pelvic floor disorders such as bladder and bowel incontinence and pelvic organ prolapse. She uses community engagement, user-centered design, and iterative ...
Monitoring of about 45,000 pregnant people receiving flu vaccines in each of 2 successive pregnancies showed no increased risk of side effects or health issues, according to a Kaiser Permanente study published September 19, 2024, in JAMA Network Open. “Our study’s findings support recommendations to give flu vaccinations to pregnant persons even if they received ...
A Kaiser Permanente Southern California study showed that 1 heart-failure medication worked best among the 3 most commonly used to prevent illness and disease among patients with chronic kidney disease and heart failure. “Beta blockers save lives in heart failure patients, but we wanted to see how this worked among patients who also had chronic ...
Gay men had shorter age-adjusted telomere length, which is a biomarker of aging, than straight men, according to a Kaiser Permanente study published in the American Journal of Epidemiology. “While everyone ages at the same rate chronologically, studies have shown that we do not age at the same rate biologically,” said the lead author on ...
High-dose and adjuvanted influenza (flu) vaccines boosted protection against flu symptoms and hospitalization for people 65 years and older during the 2022-2023 flu season compared to the standard flu vaccine. The study was published on August 21, 2024, in Clinical Infectious Diseases. “Our research showed that there were advantages for older people to receive high-dose ...
In our newest edition of IMPACT, we share stories of 2 recently released studies about flu vaccines. One looks at which vaccines are best for seniors, while the other assesses the safety of flu vaccines for women with closely spaced pregnancies. Another article examines research that found that gay men had shorter age-adjusted telomere length, which is a biomarker of aging, than straight men. Read also about research showing that beta blockers aren’t all the same for patients with heart failure and chronic kidney disease. The Q&A is with a researcher and physician who specializes in an often under-discussed issue: pelvic floor disorders. We wrap up with links to recent news articles on our research, including one in the New York Times.
Investigators with the Division of Biostatistics Research collaborate closely with scientists from the department’s other scientific divisions, as well as physician researchers at medical centers across Kaiser Permanente Southern California. They provide expertise and guidance on study design, power and sample size calculations, data management, data analysis and interpretation, and statistical methodology.
Investigators from the division have expertise in study design and data analysis for observational studies and clinical trials to address study questions. Their expertise spans standard and modern methods that deal with complex and big data for population and causal inferences as well as disease prediction.
Each division has at least one dedicated collaborative biostatistician research scientist assigned to provide statistical guidance on its research studies. In addition, one of the collaborative biostatistician researcher scientists leads the Regional Research Statistical Support team, which supports medical center-based researchers.