As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. John J. Sim is a nephrologist and clinical researcher at the Kaiser Permanente Los Angeles Medical Center. For over 13 years, Dr. Sim has studied the large, diverse membership of Kaiser Permanente Southern California by using electronic databases, disease registries, and pharmacy analytic information. His research focus is on population-based approaches to the treatment of chronic kidney disease, evaluation of the comorbidities and risk factors for CKD, and study of CKD-related outcomes such ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
Dr. Hui Zhou is the biostatistician lead in the Division of Epidemiologic Research for the Department of Research & Evaluation. There she collaborates with epidemiologists and clinical investigators on research studies ranging from conditions like hypertension, diabetes, chronic kidney disease, cardiovascular disease, and bone fractures. Dr. Zhou has extensive research experience in prediction model development ...
A Kaiser Permanente study found that the PREVENT cardiovascular risk equation had strong overall ability to predict 10-year cardiovascular disease risk in Asian, Native Hawaiian, and Other Pacific Islander adults. However, its accuracy differed across specific Asian ethnic subgroups and showed consistent patterns of over- and under-estimating when grouping by race and ethnicity. The study ...
For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation with MS. However, new research from Kaiser Permanente ...
For years, researchers have known that many people struggle to lose the weight they gain during pregnancy. Up to 1 in 4 individuals retain at least 10 pounds 1 to 2 years after giving birth, and this lingering weight can raise their long‑term risk of hypertension, cardiovascular disease, and other metabolic problems. Despite the importance ...
Wildfire smoke has increasingly been recognized as a serious public health threat. Now, 2 new Kaiser Permanente studies in Southern California have examined how health risks for both young and old people might be associated with exposure. One study showed that long-term exposure increased the risk of death among older adults, while another found that ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
The Division of Clinician Research provides support and resources for researchers who maintain clinical practices while building their own research portfolios. Key goals include fostering collaboration among clinician researchers, expanding research education, and promoting research that has the potential to transform care and improve the health of our communities.
The division, which was established in 2023, provides administrative support to the Regional Research Committee and the Clinician Investigator Program and manages a team of biostatisticians dedicated to physician research. It co-leads the Care Improvement Research Team, a group that brings together clinicians and research scientists to answer questions with the potential to change practice.
The division actively engages with various collaborators throughout the organization and is working to establish an interconnected network of clinicians, scientists, educators, administrators, and leaders who will work together to drive clinically impactful change through research.