As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Hui Xue is a nephrologist at the Kaiser Permanente San Diego Medical Center and the regional nephrology research chair for Kaiser Permanente Southern California. The goals of Dr. Xue’s research are to improve survival and the quality of life for patients with chronic kidney disease and those who are dependent on dialysis because they generally have higher rates of cardiovascular morbidity and mortality.
Dr. Xue has an educational foundation in cell biology as a Howard Hughes Fellow. ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
An RSV vaccine continued to protect adults aged 60 and older against RSV-related hospitalization and emergency department visits for at least 3 seasons after vaccination, according to a new study by Kaiser Permanente in Southern California. RSV, or respiratory syncytial virus, is a common respiratory virus that can cause serious illness, hospitalization, and even death ...
Casey Luc, PhD, MPH, an epidemiologist with expertise in HIV epidemiology in underserved communities, is the fifth Centers for Disease Control and Prevention Epidemic Intelligence Service officer to train with Kaiser Permanente Southern California’s Department of Research & Evaluation. Before joining Kaiser Permanente, he served as a health scientist contractor in the Syndemic Infectious Diseases ...
Kevin Yu, PhD, is a postdoctoral research fellow in the Department of Research & Evaluation at Kaiser Permanente Southern California. He earned his PhD in health informatics from Northwestern University, where his work focused on pharmacoepidemiology and health informatics. His research focuses on cardiovascular disease and dementia, with a particular interest in target trial emulation ...
Managing Type 2 diabetes can be challenging. Food choices matter, but healthy options aren’t always easy to afford or find. A Kaiser Permanente study found that adults with diabetes who were on Medicaid improved their blood sugar when they received healthy grocery deliveries at home. ...
For carefully selected patients, receiving advanced-level care at home after heart failure may be just as safe and effective as staying in the hospital, a new Kaiser Permanente Southern California study shows. The study, published on July 16, 2026, in JAMA Network Open, examined adults hospitalized for acute heart failure. Researchers compared patients who continued ...
From food deliveries that help people manage diabetes to vaccines that provide lasting protection, the latest issue of IMPACT highlights research making a real difference in people’s lives. In honor of National Postdoc Appreciation Week, the newsletter also introduces the department’s newest postdoctoral researcher and newest Epidemic Intelligence Service officer. The issue also features studies on advanced heart failure care delivered safely at home and showcases national media coverage of Kaiser Permanente research.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.