About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Adam Sharp headshot
Adam L. Sharp, MD, MSc
Research Scientist II
Division of Health Services Research & Implementation Science

Dr. Adam Sharp is an emergency physician at the Kaiser Permanente Los Angeles Medical Center and a research scientist at the Department of Research & Evaluation. He is an assistant professor in the Department of Health Systems Science of the Kaiser Permanente Bernard J. Tyson School of Medicine and was recently named the school’s senior advisor academic affairs. Dr. Sharp also leads the Care Improvement Research Team in the Department of Research & Evaluation, which aims to improve ...

Featured Video

Advancing treatments through clinical trials

Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)


Featured Image of News Story Titled: COVID-related hospitalizations are rare after Paxlovid treatment

COVID-related hospitalizations are rare after Paxlovid treatment

In December 2021, the Pfizer-BioNTech medication Paxlovid received emergency authorization as a treatment to prevent severe health problems from COVID-19 that could lead to hospitalization and death. But recently, small studies with less than a dozen people began to show up in the media linking the medication to a rebound in COVID-19 symptoms following recovery. ...

Omicron variant infections less severe than delta

A study of patients at Kaiser Permanente in Southern California showed that when both the delta and omicron variants were circulating in December 2021, patients who had SARS-CoV-2 infections with the omicron variant had substantially less risk of severe illness and shorter hospital stays than those infected with the delta variant. The study was published ...

New approach reduces colon cancer deaths

A study published June 6, 2022,  in The Joint Commission Journal on Quality and Patient Safety showed that a comprehensive approach to improving colon cancer care at Kaiser Permanente in Southern California resulted in a 24% decrease in mortality over 7 years. “If a new drug or surgical procedure reduced deaths this dramatically, it would ...

Clinical research center opens at Los Angeles Medical Center

A new dedicated clinical research space at the Kaiser Permanente Los Angeles Medical Center provides researchers and staff with expanded opportunities to bring groundbreaking clinical research to Kaiser Permanente Southern California members. Located on the first floor of 1505 N. Edgemont on the medical center campus, the 1,400-square-foot Kaiser Permanente Clinical Research Center at Los ...

5 questions for … Dr. William Towner

William Towner, MD, FACP, FIDSA, is the regional physician director for the Division of Clinical Trials and leads the Clinician Investigator Program for the Southern California Permanente Medical Group. He also serves in a leadership role for HIV services at Kaiser Permanente Southern California. He was extensively involved in research on infectious diseases since 2000 ...


Featured Division

Health Services Research & Implementation Science

Our health services researchers bring together scientific and clinical expertise to find better ways to improve care.

Investigators with the Division of Health Services Research & Implementation Science study how care is delivered, identify opportunities for care improvement, and implement new approaches for organizing and delivering health services. The division brings together scientists with diverse expertise and training, including emergency medicine, epidemiology, health services research, implementation science, internal medicine, nursing, pharmaceutical economics, and pulmonology.

The division is home to the Care Improvement Research Team, a research team embedded within Kaiser Permanente Southern California’s quality improvement ecosystem. The team works closely with clinical and operational partners at Kaiser Permanente Southern California to identify, prioritize, and solve problems related to quality and affordability. Its goal is to reduce unnecessary practice variation, improve affordability, and transform care.