About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Navdeep Sangha headshot
Navdeep Sangha, MD
Principal Investigator

Neurology
Clinical.Trials@kp.org

Dr. Navdeep Sangha is a vascular neurologist and co-assistant chief of Neurology at the Kaiser Permanente Los Angeles Medical Center. He is the director of the Kaiser Permanente Southern California Tele-Stroke Program and the regional stroke lead for the Southern California Permanente Medical Group.

Dr. Sangha is a principal investigator for stroke clinical trials at the Los Angeles Medical Center, and strives to increase stroke prevention and treatment trial access to patients throughout ...

Featured Video

Research showing value of exercise before COVID-19 diagnosis earns special recognition

Being active can lower your risk of getting seriously ill with COVID, regardless of your race or the chronic conditions you may have, according to research published last year in the American Journal of Preventive Medicine.

The Kaiser Permanente Southern California findings were important, impactful, and influential. As a result, the journal editors chose the research article, “Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups,” as the American Journal of Preventive Medicine 2023 Article of the Year.

News

Featured Image of News Story Titled: Good news for people newly diagnosed with MOGAD: Study finds low relapse risk

Good news for people newly diagnosed with MOGAD: Study finds low relapse risk

People newly diagnosed with myelin oligodendrocyte glycoprotein antibody-associated disease, or MOGAD, generally had a low risk of relapse and lasting disability, according to a Kaiser Permanente study. Researchers from Kaiser Permanente in Southern California followed 69 children and adults diagnosed at their first MOGAD attack and found that more than 80% fully recovered, while just ...

Ultraprocessed foods linked to body fat gain in children

Children who ate more ultraprocessed foods showed stronger activity in a part of the brain involved in reward, and that brain response was linked to greater gains in body fat over the following year, a new study found. The study — published October 2026 in JAMA Network Open — followed 46 children ages 7 to ...

No increased stroke risk found after COVID-19 and flu vaccinations

A large multisite study found that bivalent mRNA COVID-19 vaccination, flu vaccination, and same-day administration of both vaccines were not associated with an increased risk of first-ever ischemic stroke. “This study found no evidence of an increased risk of ischemic stroke following bivalent COVID-19 vaccination, influenza vaccination, or receiving both vaccines on the same day,” ...

RSV vaccine protects older adults for at least 3 seasons

An RSV vaccine continued to protect adults aged 60 and older against RSV-related hospitalization and emergency department visits for at least 3 seasons after vaccination, according to a new study by Kaiser Permanente in Southern California. RSV, or respiratory syncytial virus, is a common respiratory virus that can cause serious illness, hospitalization, and even death ...

Five questions for Dr. Casey Luc

Casey Luc, PhD, MPH, an epidemiologist with expertise in HIV epidemiology in underserved communities, is the fifth Centers for Disease Control and Prevention Epidemic Intelligence Service officer to train with Kaiser Permanente Southern California’s Department of Research & Evaluation. Before joining Kaiser Permanente, he served as a health scientist contractor in the Syndemic Infectious Diseases ...

Featured Division

Clinical Trials Research

The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.

The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.