Implementation Science studies
A Non-Inferiority Comparative Effectiveness Trial of Home-Based Palliative Care in Older Adults (HomePal)
The aim of this pragmatic trial is to compare the effects of a standard home-based palliative care (HBPC) model to a more efficient tech-supported model that includes remote physician supervision/consultation on patient symptom burden and days spent at home in the last 6 months of life and family caregiving preparedness.
Principal Investigator:Huong Q. Nguyen, PhD, RN
Funding Source:Patient-Centered Outcomes Research Institute (PCORI)
Funding Years:2018 - 2022
An Evaluation of the National Zero Suicide Model across Learning Healthcare Systems
Our project seeks to develop metrics to measure fidelity and outcomes for the National Zero Suicide Model components implemented in each system using electronic health records and insurance claims data sources that are easily extractable and generalizable to other systems. Then, we propose to use these metrics to conduct fidelity and outcome evaluation of the various Zero Suicide Initiative approaches in each system using Interrupted Time Series Designs, which are among the strongest, pragmatic designs appropriate for evaluating care system intervention and policy changes in ‘Learning Healthcare Systems.’ We hypothesize that the implementation of various National Zero Suicide Model components will significantly reduce suicidal behavior within and across the participating systems. We seek to accomplish the following aims: 1) Collaborate with health system leaders to develop EHR metrics to measure specific quality improvement targets and care processes tailored to local Zero Suicide Initiative implementation; 2) examine the fidelity of the specific Zero Suicide Initiative care processes implemented in each system; and 3) investigate suicide attempt and mortality outcomes within and across Zero Suicide Initiative healthcare system models.
Site Principal Investigator:Karen J. Coleman, PhD, MS
Funding Source:National Institute of Mental Health (NIMH)
Funding Years:2017 - 2022
Developing tailored de-implementation strategies to reduce use of low-value cancer care services
The goal of this mixed methods study is to develop and test interventions to reduce use of surveillance biomarkers for early stage breast cancer patients.
Principal Investigator:Erin E. Hahn, PhD, MPH
Funding Source:Kaiser Permanente, Southern California
Funding Years:2014 - 2015
Program in Health Services Research and Implementation Science (HSR)
This funding supports infrastructure development and operationally focused research for a program in health services research and implementation science.
Principal Investigator:Michael K. Gould, MD, MS
Funding Source:Kaiser Foundation Hospitals, Inc. (KFH)
Translation of a Lung Cancer Palliative Care Intervention for Clinical Practice
The purpose of this study is to test the dissemination of a Palliative Care Intervention (PCI) for patients with non-small cell lung cancer (NSCLC) and their primary family caregivers (FCG)