Genetics of Beta Cell Failure in Mexican Americans: Phase II (Beta Gene II)
This application is proposed to call back ~400 individuals in our previous cross-sectional BetaGene cohort study (NIDDK 61628) and re-test them for phenotypes. Analysis will be conducted to determine which genes and how they interact with each other to impact the longitudinal changes in beta-cell function and other T2DM related traits.
Principal Investigator:Anny Hui Xiang, PhD, MS
Funding Source:National Institutes of Health (NIH)
Funding Years:2009 - 2014
Observational Study of the Epidemiology in Clinical Outcomes of Breast Cancer in Women with BRCA Mutations
This cohort study examines the long-term clinical outcomes of women with breast cancer who are BRCA mutation carriers.
Principal Investigator:Reina Haque, PhD, MPH
Funding Years:2015 - 2018
Physiologic Consequence of Genetic Variation (BetaGene III)
The over-arching goal of this study is to assess the physiologic effect of genetic variation in humans and determine how variation in genes alters physiologic processes to contribute to diabetes pathogenesis.