Adherence to statins and lipid control in patients with coronary artery disease
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
Southern California Permanente Medical Group (SCPMG)
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| Funding Years:
2013-2013 |
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The goals of this project are to identify potential patient, physician and healthcare system factors associated with changes in adherence to statin therapy over time in patients with coronary artery disease and to assess the effect of changes in adherence to statin therapy on LDL-c and risk of cardiovascular disease events. |
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Impact of medication therapy discontinuation on glycemic control and health care utilization in patients with diabetes
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
Merck & Co., Inc.
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| Funding Years:
2013-2014 |
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The goals of the proposed study are to evaluate the frequency of medication therapy discontinuation among adults with diabetes prescribed two oral antihyperglycemic agents and to identify patient and physician factors associated with therapy discontinuation. |
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Analysis of device shock patterns among patients with implantable cardiac defibrillators (ICDs)
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
American College of Cardiology
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| Funding Years:
2011-2014 |
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The major goal of this project is to gain understanding of the patterns and appropriations of device shocks among patients undergoing ICD implantation for primary prevention of sudden cardiac death. |
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Air Pollution, Subclinical CVD and Inflammatory Markers in the SEARCH Cohort
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Kristi Reynolds, PhD, MPH, Site Principal Investigator
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Funding source:
National Institute of Environmental Health Sciences (NIEHS)
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| Funding Years:
2011-2015 |
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The major goal of this study is to examine the impact of air pollution on inflammatory processes and the development of subclinical cardiovascular disease in a high-risk population of youth across the U.S. |
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HMO Research Network Cardiovascular Research Network (CVRN)
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Kristi Reynolds, PhD, MPH, Site Principal Investigator
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Funding source:
National Institutes of Health (NIH)
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| Funding Years:
2007-2013 |
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The purpose of this program is to establish a collaborative CVRN among 15 member plans of the HMO Research Network to create a unique national resource that leverages the network’s CV expertise, diverse community-based study populations, and rich electronic data systems. |
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www.cvrn.org
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The Developing Evidence to Inform Decisions about Effectiveness-2 (DEcIDE-2) Network
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Kristi Reynolds, PhD, MPH, Co-Investigator
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Funding source:
Agency for Healthcare Research and Quality (AHRQ)
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| Funding Years:
2010-2013 |
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The DEcIDE-2 network supports AHRQ's response to the Medicare Modernization Act's mandates for comparative effectiveness and safety research. The Network develops scientific evidence and methodologies about the outcomes, comparative clinical effectiveness, safety, and appropriateness of health care items and services for improving the quality, effectiveness, and efficiency of healthcare. |
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Automated Outreach for Prescription Refill Reminders: Prinzide Medications
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
Kaiser Permanente
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The overall objective of the proposed study is to evaluate a low-cost outreach program of automated prescription refill reminder calls on refill pick-up rates, medication adherence and blood pressure control. |
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Using Telephonic Outreach to Improve Blood Pressure Control of a Large Population of Patients with Hypertension
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Kristi Reynolds, PhD, MPH, Co-Investigator
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Funding source:
Kaiser Permanente
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The overall objective of the proposed study is to evaluate a low-cost automated telephonic outreach program advising patients to have their blood pressure checked at their Primary Care Physician’s office. |
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Prevalence And Characteristics Of Pre-Diabetes In A Clinical Setting
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
Kaiser Permanente
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The primary objectives of this study are to describe the prevalence of pre-diabetes among adult members in the Kaiser Permanente Southern California region over a 10 year period and to determine the incidence of diabetes among those with pre-diabetes. |
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SEARCH for Diabetes in Youth Phase 3: Registry and Cohort Study, California Center
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
Centers for Disease Control and Prevention (CDC)
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| Funding Years:
2010-2015 |
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This multi-center study aims to ascertain incident diabetes cases among youth age < 20 years through 2014 to estimate trends in incidence of diabetes mellitus in youth; conduct longitudinal follow-up of incident cases diagnosed in 2002-2006 and 2008 to document the evolution of diabetes according to clinical and biochemical factors; measures quality of quality and barriers to care; and develop and validate efficient sustainable surveillance approaches for childhood diabetes that can be used for public health surveillance. (1U18DP002714) |
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http://www.searchfordiabetes.org
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Longitudinal Studies of Implantable Cardioverter Defibrillators for Primary Prevention in Community Practice: Clinical Characteristics, Shocks, Outcomes, and Cost
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Kristi Reynolds, PhD, MPH, Site Principal Investigator
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Funding source:
Agency for Healthcare Research and Quality (AHRQ)
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| Funding Years:
2009-2014 |
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Implantable cardioverter defibrillators (ICDs) are efficacious in reducing sudden cardiac death in select high-risk patients with left ventricular systolic dysfunction in the setting of randomized clinical trials. However, little is known about the patterns of use and longitudinal outcomes of ICDs for primary prevention in “real world” practice, which often bears little resemblance to the clinical trials environment. The overall objective of this study is to gain understanding of the patterns and appropriateness of device shocks among patients undergoing ICD implantation for primary prevention of sudden cardiac death. |
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http://www.cvrn.org/projects/principal/ICDs.html
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Validation of the Osteoporosis Specific Morisky Medication Adherence Scale
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
Amgen, Inc.
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| Funding Years:
2010-2013 |
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The major goal of this project is to evaluate the psychometric properties of the Osteoporosis Specific Morisky Medication Adherence Scale in a population of women with post-menopausal osteoporosis. |
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Automated Outreach to Increase Adherence to Cholesterol Lowering Medications in Patients Who Did Not Fill a New Prescription
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Kristi Reynolds, PhD, MPH, Co-Investigator
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Funding source:
Merck & Co., Inc.
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| Funding Years:
2010-2012 |
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The major goal of this project is to test the effectiveness of a low-cost, generalizable intervention to improve patient adherence to newly prescribed medications to lower cholesterol. |
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Optimizing Risk Stratification and Comparative Effectiveness Research for Atrial Fibrilliation
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Kristi Reynolds, PhD, MPH, Site Principal Investigator
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Funding source:
National Heart, Lung, and Blood Institute (NHLBI)
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| Funding Years:
2009-2012 |
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The major goals of this project are to develop a collaboration of population-based researchers as well as a research platform using a contemporary cohort of about 40,000 adults with atrial fibrillation to improve comparative effectiveness studies, risk stratification of outcomes and the planning and conduct of future observational studies and randomized trials for atrial fibrillation. |
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Medical Benefits of Implementing a Collaborative Care Depression Screening and Treatment Program
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Kristi Reynolds, PhD, MPH, Co-Investigator
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Funding source:
Southern California Permanente Medical Group (SCPMG)
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To examine the effect of screening for depression on caridovascular disease outcomes and to evaluate the impact of a depression care management program in a primary care setting for cardiovascular disease patients. |
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Medical Care and Utilization as a Function of Body Mass Index (BMI)
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Kristi Reynolds, PhD, MPH, Principal Investigator
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Funding source:
Kaiser Permanente
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Recent data indicate that obese individuals experience healthcare disparities that include delays or avoidance in receiving preventive care. The increased risk of chronic diseases such as osteoarthritis, diabetes, and cardiovascular disease among obese individuals make delays and avoidance of medical care dangerous. The identification of barriers to adequate medical care and preventive services is of extreme importance in order to improve care and outcomes among obese individuals. The objectives of this study are to examine the association between body mass index (BMI), demographics, co-morbidities, service utilization, and quality of care. |
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